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The unravelling of the ubiquitin system.
Ciechanover A. Ciechanover A. Nat Rev Mol Cell Biol. 2015 May;16(5):322-4. doi: 10.1038/nrm3982. Nat Rev Mol Cell Biol. 2015. PMID: 25907614 Review.
Purification and characterization of a novel protein that is required for degradation of N-alpha-acetylated proteins by the ubiquitin system.
Gonen H, Schwartz AL, Ciechanover A. Gonen H, et al. Among authors: ciechanover a. J Biol Chem. 1991 Oct 15;266(29):19221-31. J Biol Chem. 1991. PMID: 1655778 Free article.
These proteins are degraded in whole lysates in a ubiquitin-dependent manner (Mayer, A. Siegel, N. R., Schwartz, A. L., and Ciechanover, A. (1989) Science 244, 1480-1483). It appears that a protein factor which is specifically required fo …
These proteins are degraded in whole lysates in a ubiquitin-dependent manner (Mayer, A. Siegel, N. R., Schwartz, A. L., …
Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation.
Orian A, Whiteside S, Israël A, Stancovski I, Schwartz AL, Ciechanover A. Orian A, et al. Among authors: ciechanover a. J Biol Chem. 1995 Sep 15;270(37):21707-14. doi: 10.1074/jbc.270.37.21707. J Biol Chem. 1995. PMID: 7665588 Free article.
The ubiquitin-proteasome proteolytic pathway.
Ciechanover A. Ciechanover A. Cell. 1994 Oct 7;79(1):13-21. doi: 10.1016/0092-8674(94)90396-4. Cell. 1994. PMID: 7923371 Review. No abstract available.
Protein synthesis elongation factor EF-1 alpha is essential for ubiquitin-dependent degradation of certain N alpha-acetylated proteins and may be substituted for by the bacterial elongation factor EF-Tu.
Gonen H, Smith CE, Siegel NR, Kahana C, Merrick WC, Chakraburtty K, Schwartz AL, Ciechanover A. Gonen H, et al. Among authors: ciechanover a. Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7648-52. doi: 10.1073/pnas.91.16.7648. Proc Natl Acad Sci U S A. 1994. PMID: 8052636 Free PMC article.
Degradation of the tumor suppressor protein p53 by the ubiquitin-mediated proteolytic system requires a novel species of ubiquitin-carrier protein, E2.
Ciechanover A, Shkedy D, Oren M, Bercovich B. Ciechanover A, et al. J Biol Chem. 1994 Apr 1;269(13):9582-9. J Biol Chem. 1994. PMID: 8144545 Free article.
The degradation is stimulated significantly by the human papillomavirus (HPV) oncoprotein E6 that associates with p53 and facilitates conjugate formation and subsequent degradation. Complex formation between E6 and p53 is promoted by a cellular protein designated E6-associ …
The degradation is stimulated significantly by the human papillomavirus (HPV) oncoprotein E6 that associates with p53 and facilitates conjug …
302 results