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N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.
Yoo YD, Mun SR, Ji CH, Sung KW, Kang KY, Heo AJ, Lee SH, An JY, Hwang J, Xie XQ, Ciechanover A, Kim BY, Kwon YT. Yoo YD, et al. Among authors: ciechanover a. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2716-E2724. doi: 10.1073/pnas.1719110115. Epub 2018 Mar 5. Proc Natl Acad Sci U S A. 2018. PMID: 29507222 Free PMC article.
Protein synthesis elongation factor EF-1 alpha is essential for ubiquitin-dependent degradation of certain N alpha-acetylated proteins and may be substituted for by the bacterial elongation factor EF-Tu.
Gonen H, Smith CE, Siegel NR, Kahana C, Merrick WC, Chakraburtty K, Schwartz AL, Ciechanover A. Gonen H, et al. Among authors: ciechanover a. Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7648-52. doi: 10.1073/pnas.91.16.7648. Proc Natl Acad Sci U S A. 1994. PMID: 8052636 Free PMC article.
Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome.
Zaaroor-Regev D, de Bie P, Scheffner M, Noy T, Shemer R, Heled M, Stein I, Pikarsky E, Ciechanover A. Zaaroor-Regev D, et al. Among authors: ciechanover a. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6788-93. doi: 10.1073/pnas.1003108107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351251 Free PMC article.
HUWE1 ubiquitinates MyoD and targets it for proteasomal degradation.
Noy T, Suad O, Taglicht D, Ciechanover A. Noy T, et al. Among authors: ciechanover a. Biochem Biophys Res Commun. 2012 Feb 10;418(2):408-13. doi: 10.1016/j.bbrc.2012.01.045. Epub 2012 Jan 18. Biochem Biophys Res Commun. 2012. PMID: 22277673
302 results