Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

275 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
The ubiquitin-proteasome proteolytic pathway.
Ciechanover A. Ciechanover A. Cell. 1994 Oct 7;79(1):13-21. doi: 10.1016/0092-8674(94)90396-4. Cell. 1994. PMID: 7923371 Review. No abstract available.
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.
Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Campanella M, Candi E, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, Di Daniele N, Dixit VM, Dynlacht BD, El-Deiry WS, Fimia GM, Flavell RA, Fulda S, Garrido C, Gougeon ML, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Joseph B, Jost PJ, Kaufmann T, Kepp O, Klionsky DJ, Knight RA, Kumar S, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lugli E, Madeo F, Malorni W, Marine JC, Martin SJ, Martinou JC, Medema JP, Meier P, Melino S, Mizushima N, Moll U, Muñoz-Pinedo C, Nuñez G, Oberst A, Panaretakis T, Penninger JM, Peter ME, Piacentini M, Pinton P, Prehn JH, Puthalakath H, Rabinovich GA, Ravichandran KS, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Shi Y, Simon HU, Stockwell BR, Szabadkai G, Tait SW, Tang HL, Tavernarakis N, Tsujimoto Y, Vanden Berghe T, Vandenabeele P, Villunger A, Wagner EF, Walczak H, White E, Wood WG, Yuan J, Zakeri Z, Zhivotovsky B, Melino G, Kroemer G. Galluzzi L, et al. Among authors: ciechanover a. Cell Death Differ. 2015 Jan;22(1):58-73. doi: 10.1038/cdd.2014.137. Epub 2014 Sep 19. Cell Death Differ. 2015. PMID: 25236395 Free PMC article. Review.
Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. ...The biochemical phenomena that accompany RCD may be harnessed to classify it into a few subtypes, which often (but …
Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate struct …
The ubiquitin proteasome system and its involvement in cell death pathways.
Bernassola F, Ciechanover A, Melino G. Bernassola F, et al. Among authors: ciechanover a. Cell Death Differ. 2010 Jan;17(1):1-3. doi: 10.1038/cdd.2009.189. Cell Death Differ. 2010. PMID: 20010850 No abstract available.
Early work on the ubiquitin proteasome system, an interview with Aaron Ciechanover. Interview by CDD.
Ciechanover A. Ciechanover A. Cell Death Differ. 2005 Sep;12(9):1167-77. doi: 10.1038/sj.cdd.4401691. Cell Death Differ. 2005. PMID: 16094393 No abstract available.
Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein-Barr virus nuclear antigen 1.
Levitskaya J, Sharipo A, Leonchiks A, Ciechanover A, Masucci MG. Levitskaya J, et al. Among authors: ciechanover a. Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12616-21. doi: 10.1073/pnas.94.23.12616. Proc Natl Acad Sci U S A. 1997. PMID: 9356498 Free PMC article.
We have investigated the influence of the repeat on this process by comparing the degradation of EBNA1, EBNA4, and Gly-Ala containing EBNA4 chimeras in a cell-free system. ...Inhibition was also achieved by insertion of a Pro-Ala coding sequence. The results suggest …
We have investigated the influence of the repeat on this process by comparing the degradation of EBNA1, EBNA4, and Gly-Ala containing EBNA4 …
Degradation of nuclear oncoproteins by the ubiquitin system in vitro.
Ciechanover A, DiGiuseppe JA, Bercovich B, Orian A, Richter JD, Schwartz AL, Brodeur GM. Ciechanover A, et al. Proc Natl Acad Sci U S A. 1991 Jan 1;88(1):139-43. doi: 10.1073/pnas.88.1.139. Proc Natl Acad Sci U S A. 1991. PMID: 1846034 Free PMC article.
Degradation of other proteins, such as superoxide dismutase, cytochrome c, enolase, RNase A, and ornithine decarboxylase, is not mediated by the ubiquitin cell-free system. ...Furthermore, the relative sensitivity to degradation of various E1A mutants in vivo is also maint …
Degradation of other proteins, such as superoxide dismutase, cytochrome c, enolase, RNase A, and ornithine decarboxylase, is not medi …
Ubiquitin-dependent degradation of certain protein substrates in vitro requires the molecular chaperone Hsc70.
Bercovich B, Stancovski I, Mayer A, Blumenfeld N, Laszlo A, Schwartz AL, Ciechanover A. Bercovich B, et al. Among authors: ciechanover a. J Biol Chem. 1997 Apr 4;272(14):9002-10. doi: 10.1074/jbc.272.14.9002. J Biol Chem. 1997. PMID: 9083024
Conjugation is catalyzed via a three-step mechanism that involves three distinct enzymes that act successively: E1, E2, and E3. ...E3, to which the substrate is specifically bound, catalyzes formation of a polyubiquitin chain that is anchored to the targeted protein …
Conjugation is catalyzed via a three-step mechanism that involves three distinct enzymes that act successively: E1, E2, and E3. ...E3 …
Purification and characterization of a novel species of ubiquitin-carrier protein, E2, that is involved in degradation of non-"N-end rule" protein substrates.
Blumenfeld N, Gonen H, Mayer A, Smith CE, Siegel NR, Schwartz AL, Ciechanover A. Blumenfeld N, et al. Among authors: ciechanover a. J Biol Chem. 1994 Apr 1;269(13):9574-81. J Biol Chem. 1994. PMID: 8144544
Like all members of the E2 family, it generates a thiol ester with ubiquitin that serves as an intermediate in the conjugation reaction. Sequence analysis revealed a significant homology to many known species of E2s. The enzyme generates multiply ubiquitinated prote …
Like all members of the E2 family, it generates a thiol ester with ubiquitin that serves as an intermediate in the conjugation reacti …
Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation.
Orian A, Whiteside S, Israël A, Stancovski I, Schwartz AL, Ciechanover A. Orian A, et al. Among authors: ciechanover a. J Biol Chem. 1995 Sep 15;270(37):21707-14. doi: 10.1074/jbc.270.37.21707. J Biol Chem. 1995. PMID: 7665588
In most cases, the transcriptional factor NF-kappa B is a heterodimer consisting of two subunits, p50 and p65, which are encoded by two distinct genes of the Rel family. p50 is translated as a precursor of 105 kDa. ...J., Goldberg, A. L., and Maniatis, T. (19 …
In most cases, the transcriptional factor NF-kappa B is a heterodimer consisting of two subunits, p50 and p65, which are encoded by t …
Purification, characterization, and rapid inactivation of thermolabile ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85.
Mayer A, Gropper R, Schwartz AL, Ciechanover A. Mayer A, et al. Among authors: ciechanover a. J Biol Chem. 1989 Feb 5;264(4):2060-8. J Biol Chem. 1989. PMID: 2914892
We have characterized a temperature sensitive cell cycle arrest mutant cell (ts85) with a thermolabile ubiquitin-activating enzyme (E1; Finley, D., Ciechanover, A., and Varshavsky, A. (1984) Cell 37, 43-55). Following incubation at the restricti …
We have characterized a temperature sensitive cell cycle arrest mutant cell (ts85) with a thermolabile ubiquitin-activating en …
275 results
Jump to page
Feedback