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The ubiquitin system.
Hershko A, Ciechanover A. Hershko A, et al. Among authors: ciechanover a. Annu Rev Biochem. 1998;67:425-79. doi: 10.1146/annurev.biochem.67.1.425. Annu Rev Biochem. 1998. PMID: 9759494 Review.
ATP-stimulated degradation of endogenous proteins in cell-free extracts of BHK 21/C13 fibroblasts. A key role for the proteinase, macropain, in the ubiquitin-dependent degradation of short-lived proteins.
DeMartino GN, McCullough ML, Reckelhoff JF, Croall DE, Ciechanover A, McGuire MJ. DeMartino GN, et al. Among authors: ciechanover a. Biochim Biophys Acta. 1991 Mar 4;1073(2):299-308. doi: 10.1016/0304-4165(91)90135-4. Biochim Biophys Acta. 1991. PMID: 1849005
Degradation of nuclear oncoproteins by the ubiquitin system in vitro.
Ciechanover A, DiGiuseppe JA, Bercovich B, Orian A, Richter JD, Schwartz AL, Brodeur GM. Ciechanover A, et al. Proc Natl Acad Sci U S A. 1991 Jan 1;88(1):139-43. doi: 10.1073/pnas.88.1.139. Proc Natl Acad Sci U S A. 1991. PMID: 1846034 Free PMC article.
Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.
Hershko A, Heller H, Elias S, Ciechanover A. Hershko A, et al. Among authors: ciechanover a. J Biol Chem. 1983 Jul 10;258(13):8206-14. J Biol Chem. 1983. PMID: 6305978
One is the ubiquitin-activating enzyme (E1), which is covalently linked to the affinity column in the presence of ATP and can be specifically eluted with AMP and pyrophosphate (Ciechanover, A., Elias, S., Heller, H., and Hershko, A. (1982) J. Biol. Chem. 257, …
One is the ubiquitin-activating enzyme (E1), which is covalently linked to the affinity column in the presence of ATP and can be specificall …
Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation.
Orian A, Whiteside S, Israël A, Stancovski I, Schwartz AL, Ciechanover A. Orian A, et al. Among authors: ciechanover a. J Biol Chem. 1995 Sep 15;270(37):21707-14. doi: 10.1074/jbc.270.37.21707. J Biol Chem. 1995. PMID: 7665588
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