Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1981 1
1991 1
1992 1
1994 2
1996 2
1997 1
1998 1
2004 1
2006 2
2007 5
2008 1
2009 2
2010 2
2011 2
2013 1
2016 1
2018 3
2019 3
2020 2
2021 3
2022 2
2023 0
Text availability
Article attribute
Article type
Publication date

Search Results

37 results
Results by year
Filters applied: . Clear all
Page 1
Cinnamonitrile Adjuvants Restore Susceptibility to β-Lactams against Methicillin-Resistant Staphylococcus aureus.
Speri E, Kim C, De Benedetti S, Qian Y, Lastochkin E, Fishovitz J, Fisher JF, Mobashery S. Speri E, et al. ACS Med Chem Lett. 2019 Jul 1;10(8):1148-1153. doi: 10.1021/acsmedchemlett.9b00169. eCollection 2019 Aug 8. ACS Med Chem Lett. 2019. PMID: 31413798 Free PMC article.
However, the emergence of methicillin-resistant S. aureus (MRSA) renders them clinically precarious. We describe a class of cinnamonitrile adjuvants that restore the activity of oxacillin (a penicillin member of the beta-lactams) against MRSA. ...
However, the emergence of methicillin-resistant S. aureus (MRSA) renders them clinically precarious. We describe a class of cinnamonitril …
Use of achiral/chiral SFC/MS for the profiling of isomeric cinnamonitrile/hydrocinnamonitrile products in chiral drug synthesis.
Alexander AJ, Staab A. Alexander AJ, et al. Anal Chem. 2006 Jun 1;78(11):3835-8. doi: 10.1021/ac060326b. Anal Chem. 2006. PMID: 16737245
A directly coupled achiral/chiral SFC/MS method has been developed for the profiling of a three-step stereoselective synthesis of cinnamonitrile and hydrocinnamonitrile intermediates. Semipurified reaction mixtures were screened in one step to determine the diastereomeric/ …
A directly coupled achiral/chiral SFC/MS method has been developed for the profiling of a three-step stereoselective synthesis of cinnamo …
Formation of mercapturic acids from acrylonitrile, crotononitrile, and cinnamonitrile by direct conjugation and via an intermediate oxidation process.
van Bladeren PJ, Delbressine LP, Hoogeterp JJ, Beaumont AH, Breimer DD, Seutter-Berlage F, van der Gen A. van Bladeren PJ, et al. Drug Metab Dispos. 1981 May-Jun;9(3):246-9. Drug Metab Dispos. 1981. PMID: 6113934
After administration of acrylonitrile, crotononitrile and cinnamonitrile to rats, two types of mercapturic acids were isolated from urine and identified by mass and NMR spectroscopy as N-acetyl-S-(2-cyanoethyl)-L-cysteine (I) and N-acetyl-S-(2-hydroxyethyl)-L-cysteine (II) …
After administration of acrylonitrile, crotononitrile and cinnamonitrile to rats, two types of mercapturic acids were isolated from u …
Characterization of the Nit6803 nitrilase homolog from the cyanotroph Pseudomonas fluorescens NCIMB 11764.
Jones LB, Wang X, Gullapalli JS, Kunz DA. Jones LB, et al. Biochem Biophys Rep. 2021 Jan 16;25:100893. doi: 10.1016/j.bbrep.2020.100893. eCollection 2021 Mar. Biochem Biophys Rep. 2021. PMID: 33506113 Free PMC article.
The two enzymes exhibit a similar substrate profile, however, for Nit11764, cinnamonitrile, was found to be an even better substrate than fumaronitrile the best substrate previously identified for Nit6803. A higher affinity for cinnamonitrile (Km 1.27 mM) compared t …
The two enzymes exhibit a similar substrate profile, however, for Nit11764, cinnamonitrile, was found to be an even better substrate …
DFT insights into superelectrophilic activation of α,β-unsaturated nitriles and ketones in superacids.
Genaev AM, Salnikov GE, Koltunov KY. Genaev AM, et al. Org Biomol Chem. 2022 Aug 31;20(34):6799-6808. doi: 10.1039/d2ob01141g. Org Biomol Chem. 2022. PMID: 35959855
However, the essence of such activation is not yet fully recognized, while a number of alternative views on the subject have been discussed at length in the literature. Here, taking the example of virtual reactions of cinnamonitrile and benzalacetone with benzene, their fe …
However, the essence of such activation is not yet fully recognized, while a number of alternative views on the subject have been discussed …
Activity-dependent fluorescent labeling of bacteria that degrade toluene via toluene 2,3-dioxygenase.
Keener WK, Watwood ME, Apel WA. Keener WK, et al. Appl Microbiol Biotechnol. 1998 Apr;49(4):455-62. doi: 10.1007/s002530051198. Appl Microbiol Biotechnol. 1998. PMID: 9615486
Alternative substrates for the toluene 2,3-dioxygenase pathway of several pseudomonads served as enzyme-activity-dependent fluorescent probes for the bacteria. Phenylacetylene and cinnamonitrile were transformed to fluorescent and brightly colored products by Pseudomonas p …
Alternative substrates for the toluene 2,3-dioxygenase pathway of several pseudomonads served as enzyme-activity-dependent fluorescent probe …
On the mechanism of Ni(ii)-promoted Michael-type hydroamination of acrylonitrile and its substituted derivatives.
Lapointe S, Zargarian D. Lapointe S, et al. Dalton Trans. 2016 Oct 12;45(40):15800-15810. doi: 10.1039/c6dt02105k. Dalton Trans. 2016. PMID: 27410777
The catalytic activities for the addition of primary amines to crotonitrile, methacrylonitrile, and cinnamonitrile were found to depend on the precursor and the amine used, as well as on the reaction time. ...We have also prepared and characterized the cationic acrylonitri …
The catalytic activities for the addition of primary amines to crotonitrile, methacrylonitrile, and cinnamonitrile were found to depe …
Controlled microwave-assisted reactions: A facile synthesis of polyfunctionally substituted phthalazines as dual EGFR and PI3K inhibitors in CNS SNB-75 cell line.
Hassan Nazmy M, Ahmed Mekheimer R, Shoman ME, Abo-Elsebaa M, Abd-Elmonem M, Usef Sadek K. Hassan Nazmy M, et al. Bioorg Chem. 2022 May;122:105740. doi: 10.1016/j.bioorg.2022.105740. Epub 2022 Mar 12. Bioorg Chem. 2022. PMID: 35298961
An efficient one-pot synthesis of polyfunctionalized phthalazines derivatives was developed by reacting ethyl 1-aryl-5-cyano-1,6-dihydro-4-methyl-6-oxo-3-pyridazine-carboxylates with cinnamonitrile derivatives and the cycloaddition reaction of thieno[3,4-d]pyridazines with …
An efficient one-pot synthesis of polyfunctionalized phthalazines derivatives was developed by reacting ethyl 1-aryl-5-cyano-1,6-dihydro-4-m …
A nitrilase from a metagenomic library acts regioselectively on aliphatic dinitriles.
Bayer S, Birkemeyer C, Ballschmiter M. Bayer S, et al. Appl Microbiol Biotechnol. 2011 Jan;89(1):91-8. doi: 10.1007/s00253-010-2831-9. Epub 2010 Aug 20. Appl Microbiol Biotechnol. 2011. PMID: 20725724
Several novel nitrilases were selected from metagenomic libraries using cinnamonitrile and a mixture of six different nitriles as substrates. ...
Several novel nitrilases were selected from metagenomic libraries using cinnamonitrile and a mixture of six different nitriles as sub …
Influence of the electronic characteristics of N-donor ligands in the excited state of heteronuclear gold(I)-copper(I) systems.
López-de-Luzuriaga JM, Monge M, Olmos ME, Pascual D, Rodríguez-Castillo M. López-de-Luzuriaga JM, et al. Inorg Chem. 2011 Aug 1;50(15):6910-21. doi: 10.1021/ic102550z. Epub 2011 Jun 30. Inorg Chem. 2011. PMID: 21718064
By reaction of the heterometallic gold-silver complexes [{AuAg(C(6)F(5))(2)(NC-Me)}(2)](n) or [{AuAg(C(6)Cl(5))(2)(NC-Me)}(2)](n) and CuCl in the presence of pyrimidine and different nitrile ligands (acetonitrile, benzonitrile, and cinnamonitrile), the heteronuclear comple …
By reaction of the heterometallic gold-silver complexes [{AuAg(C(6)F(5))(2)(NC-Me)}(2)](n) or [{AuAg(C(6)Cl(5))(2)(NC-Me)}(2)](n) and CuCl i …
37 results