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Tumor-infiltrating lymphocytes: apparently good for melanoma patients. But why?
Cipponi A, Wieers G, van Baren N, Coulie PG. Cipponi A, et al. Cancer Immunol Immunother. 2011 Aug;60(8):1153-60. doi: 10.1007/s00262-011-1026-2. Epub 2011 May 7. Cancer Immunol Immunother. 2011. PMID: 21553145 Review.
Peripheral blood lymphocytes genetically modified to express the self/tumor antigen MAGE-A3 induce antitumor immune responses in cancer patients.
Fontana R, Bregni M, Cipponi A, Raccosta L, Rainelli C, Maggioni D, Lunghi F, Ciceri F, Mukenge S, Doglioni C, Colau D, Coulie PG, Bordignon C, Traversari C, Russo V. Fontana R, et al. Among authors: cipponi a. Blood. 2009 Feb 19;113(8):1651-60. doi: 10.1182/blood-2008-07-168666. Epub 2008 Dec 12. Blood. 2009. PMID: 19074732 Clinical Trial.
Neogenesis of lymphoid structures and antibody responses occur in human melanoma metastases.
Cipponi A, Mercier M, Seremet T, Baurain JF, Théate I, van den Oord J, Stas M, Boon T, Coulie PG, van Baren N. Cipponi A, et al. Cancer Res. 2012 Aug 15;72(16):3997-4007. doi: 10.1158/0008-5472.CAN-12-1377. Epub 2012 Jul 31. Cancer Res. 2012. PMID: 22850419 Free article.
Lymphocytes genetically modified to express tumor antigens target DCs in vivo and induce antitumor immunity.
Russo V, Cipponi A, Raccosta L, Rainelli C, Fontana R, Maggioni D, Lunghi F, Mukenge S, Ciceri F, Bregni M, Bordignon C, Traversari C. Russo V, et al. Among authors: cipponi a. J Clin Invest. 2007 Oct;117(10):3087-96. doi: 10.1172/JCI30605. J Clin Invest. 2007. PMID: 17885685 Free PMC article.
Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus.
Aiuti A, Turchetto L, Cota M, Cipponi A, Brambilla A, Arcelloni C, Paroni R, Vicenzi E, Bordignon C, Poli G. Aiuti A, et al. Among authors: cipponi a. Blood. 1999 Jul 1;94(1):62-73. Blood. 1999. PMID: 10381499
Direct effects of polymyxin B on human dendritic cells maturation. The role of IkappaB-alpha/NF-kappaB and ERK1/2 pathways and adhesion.
Valentinis B, Bianchi A, Zhou D, Cipponi A, Catalanotti F, Russo V, Traversari C. Valentinis B, et al. Among authors: cipponi a. J Biol Chem. 2005 Apr 8;280(14):14264-71. doi: 10.1074/jbc.M410791200. Epub 2005 Jan 25. J Biol Chem. 2005. PMID: 15671028
High-performance liquid chromatographic purification and capillary electrophoresis quantification of the chemokine stromal cell-derived factor-1.
Arcelloni C, Aiuti A, Cipponi A, Paroni R. Arcelloni C, et al. Among authors: cipponi a. J Chromatogr B Biomed Sci Appl. 1999 Jun 11;729(1-2):369-74. doi: 10.1016/s0378-4347(99)00154-1. J Chromatogr B Biomed Sci Appl. 1999. PMID: 10410964
Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors.
Aiuti A, Tavian M, Cipponi A, Ficara F, Zappone E, Hoxie J, Peault B, Bordignon C. Aiuti A, et al. Among authors: cipponi a. Eur J Immunol. 1999 Jun;29(6):1823-31. doi: 10.1002/(SICI)1521-4141(199906)29:06<1823::AID-IMMU1823>3.0.CO;2-B. Eur J Immunol. 1999. PMID: 10382744
Monogenic and polygenic determinants of sarcoma risk: an international genetic study.
Ballinger ML, Goode DL, Ray-Coquard I, James PA, Mitchell G, Niedermayr E, Puri A, Schiffman JD, Dite GS, Cipponi A, Maki RG, Brohl AS, Myklebost O, Stratford EW, Lorenz S, Ahn SM, Ahn JH, Kim JE, Shanley S, Beshay V, Randall RL, Judson I, Seddon B, Campbell IG, Young MA, Sarin R, Blay JY, O'Donoghue SI, Thomas DM; International Sarcoma Kindred Study. Ballinger ML, et al. Among authors: cipponi a. Lancet Oncol. 2016 Sep;17(9):1261-71. doi: 10.1016/S1470-2045(16)30147-4. Epub 2016 Aug 4. Lancet Oncol. 2016. PMID: 27498913
High frequency of germline TP53 mutations in a prospective adult-onset sarcoma cohort.
Mitchell G, Ballinger ML, Wong S, Hewitt C, James P, Young MA, Cipponi A, Pang T, Goode DL, Dobrovic A, Thomas DM; International Sarcoma Kindred Study. Mitchell G, et al. Among authors: cipponi a. PLoS One. 2013 Jul 22;8(7):e69026. doi: 10.1371/journal.pone.0069026. Print 2013. PLoS One. 2013. PMID: 23894400 Free PMC article.
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