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Circulating tumor cells from prostate cancer patients interact with E-selectin under physiologic blood flow.
Gakhar G, Navarro VN, Jurish M, Lee GY, Tagawa ST, Akhtar NH, Seandel M, Geng Y, Liu H, Bander NH, Giannakakou P, Christos PJ, King MR, Nanus DM. Gakhar G, et al. PLoS One. 2013 Dec 27;8(12):e85143. doi: 10.1371/journal.pone.0085143. eCollection 2013. PLoS One. 2013. PMID: 24386459 Free PMC article. Clinical Trial.
Several studies provide evidence that prostate cancer (PCa) cell tethering and rolling on microvascular endothelium via E-selectin/E-selectin ligand interactions under shear flow theoretically promote extravasation and contr …
Several studies provide evidence that prostate cancer (PCa) cell tethering and rolling on microvascular endothelium via E …
In vitro method to observe E-selectin-mediated interactions between prostate circulating tumor cells derived from patients and human endothelial cells.
Gakhar G, Bander NH, Nanus DM. Gakhar G, et al. J Vis Exp. 2014 May 15;(87):51468. doi: 10.3791/51468. J Vis Exp. 2014. PMID: 24894373 Free PMC article.
However, to observe and study interactions with rare cells such as circulating tumor cells (CTCs), certain changes are required to be made to the conventional flow chamber assembly. ...In the present report, we describe a unique method to …
However, to observe and study interactions with rare cells such as circulating tumor cells (CTCs), certai …