Cirrito JR - Search Results

1

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model.

Sanchez PE, Zhu L, Verret L, Vossel KA, Orr AG, Cirrito JR, Devidze N, Ho K, Yu GQ, Palop JJ, Mucke L. Sanchez PE, et al. Among authors: cirrito jr. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):E2895-903. doi: 10.1073/pnas.1121081109. Epub 2012 Aug 6. Proc Natl Acad Sci U S A. 2012. PMID: 22869752 Free PMC article.

2

Pimavanserin, a 5HT_2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease.

Yuede CM, Wallace CE, Davis TA, Gardiner WD, Hettinger JC, Edwards HM, Hendrix RD, Doherty BM, Yuede KM, Burstein ES, Cirrito JR. Yuede CM, et al. Among authors: cirrito jr. J Neurochem. 2021 Mar;156(5):658-673. doi: 10.1111/jnc.15260. Epub 2021 Jan 10. J Neurochem. 2021. PMID: 33278025 Free PMC article.

3

Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein.

Zerbinatti CV, Wozniak DF, Cirrito J, Cam JA, Osaka H, Bales KR, Zhuo M, Paul SM, Holtzman DM, Bu G. Zerbinatti CV, et al. Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):1075-80. doi: 10.1073/pnas.0305803101. Epub 2004 Jan 19. Proc Natl Acad Sci U S A. 2004. PMID: 14732699 Free PMC article.

4

Acute stress increases interstitial fluid amyloid-beta via corticotropin-releasing factor and neuronal activity.

Kang JE, Cirrito JR, Dong H, Csernansky JG, Holtzman DM. Kang JE, et al. Among authors: cirrito jr. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10673-8. doi: 10.1073/pnas.0700148104. Epub 2007 Jun 5. Proc Natl Acad Sci U S A. 2007. PMID: 17551018 Free PMC article.

5

Cerebrovascular dysfunction in amyloid precursor protein transgenic mice: contribution of soluble and insoluble amyloid-beta peptide, partial restoration via gamma-secretase inhibition.

Han BH, Zhou ML, Abousaleh F, Brendza RP, Dietrich HH, Koenigsknecht-Talboo J, Cirrito JR, Milner E, Holtzman DM, Zipfel GJ. Han BH, et al. Among authors: cirrito jr. J Neurosci. 2008 Dec 10;28(50):13542-50. doi: 10.1523/JNEUROSCI.4686-08.2008. J Neurosci. 2008. PMID: 19074028 Free PMC article.

6

Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans.

Cirrito JR, Disabato BM, Restivo JL, Verges DK, Goebel WD, Sathyan A, Hayreh D, D'Angelo G, Benzinger T, Yoon H, Kim J, Morris JC, Mintun MA, Sheline YI. Cirrito JR, et al. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14968-73. doi: 10.1073/pnas.1107411108. Epub 2011 Aug 22. Proc Natl Acad Sci U S A. 2011. PMID: 21873225 Free PMC article.

7

Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice.

Kraft AW, Hu X, Yoon H, Yan P, Xiao Q, Wang Y, Gil SC, Brown J, Wilhelmsson U, Restivo JL, Cirrito JR, Holtzman DM, Kim J, Pekny M, Lee JM. Kraft AW, et al. Among authors: cirrito jr. FASEB J. 2013 Jan;27(1):187-98. doi: 10.1096/fj.12-208660. Epub 2012 Oct 4. FASEB J. 2013. PMID: 23038755 Free PMC article.

8

Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease.

Born HA, Kim JY, Savjani RR, Das P, Dabaghian YA, Guo Q, Yoo JW, Schuler DR, Cirrito JR, Zheng H, Golde TE, Noebels JL, Jankowsky JL. Born HA, et al. Among authors: cirrito jr. J Neurosci. 2014 Mar 12;34(11):3826-40. doi: 10.1523/JNEUROSCI.5171-13.2014. J Neurosci. 2014. PMID: 24623762 Free PMC article.

9

Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease.

Fowler SW, Chiang AC, Savjani RR, Larson ME, Sherman MA, Schuler DR, Cirrito JR, Lesné SE, Jankowsky JL. Fowler SW, et al. Among authors: cirrito jr. J Neurosci. 2014 Jun 4;34(23):7871-85. doi: 10.1523/JNEUROSCI.0572-14.2014. J Neurosci. 2014. PMID: 24899710 Free PMC article.

10

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease.

Roh JH, Jiang H, Finn MB, Stewart FR, Mahan TE, Cirrito JR, Heda A, Snider BJ, Li M, Yanagisawa M, de Lecea L, Holtzman DM. Roh JH, et al. Among authors: cirrito jr. J Exp Med. 2014 Dec 15;211(13):2487-96. doi: 10.1084/jem.20141788. Epub 2014 Nov 24. J Exp Med. 2014. PMID: 25422493 Free PMC article.

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