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A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation.
Özçam M, Oh JH, Tocmo R, Acharya D, Zhang S, Astmann TJ, Heggen M, Ruiz-Ramírez S, Li F, Cheng CC, Vivas E, Rey FE, Claesen J, Bugni TS, Walter J, van Pijkeren JP. Özçam M, et al. Among authors: claesen j. Cell Host Microbe. 2022 Jun 8;30(6):824-835.e6. doi: 10.1016/j.chom.2022.03.033. Epub 2022 Apr 19. Cell Host Microbe. 2022. PMID: 35443156 Free article.
A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis.
Osborn LJ, Schultz K, Massey W, DeLucia B, Choucair I, Varadharajan V, Banerjee R, Fung K, Horak AJ 3rd, Orabi D, Nemet I, Nagy LE, Wang Z, Allende DS, Willard BB, Sangwan N, Hajjar AM, McDonald C, Ahern PP, Hazen SL, Brown JM, Claesen J. Osborn LJ, et al. Among authors: claesen j. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2202934119. doi: 10.1073/pnas.2202934119. Epub 2022 Nov 23. Proc Natl Acad Sci U S A. 2022. PMID: 36417437 Free PMC article.
Disruption of the Gut Microbiota Confers Cisplatin Resistance in Epithelial Ovarian Cancer.
Chambers LM, Esakov Rhoades EL, Bharti R, Braley C, Tewari S, Trestan L, Alali Z, Bayik D, Lathia JD, Sangwan N, Bazeley P, Joehlin-Price AS, Wang Z, Dutta S, Dwidar M, Hajjar A, Ahern PP, Claesen J, Rose P, Vargas R, Brown JM, Michener CM, Reizes O. Chambers LM, et al. Among authors: claesen j. Cancer Res. 2022 Dec 16;82(24):4654-4669. doi: 10.1158/0008-5472.CAN-22-0455. Cancer Res. 2022. PMID: 36206317 Free PMC article.
Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut.
Bell A, Brunt J, Crost E, Vaux L, Nepravishta R, Owen CD, Latousakis D, Xiao A, Li W, Chen X, Walsh MA, Claesen J, Angulo J, Thomas GH, Juge N. Bell A, et al. Among authors: claesen j. Nat Microbiol. 2019 Dec;4(12):2393-2404. doi: 10.1038/s41564-019-0590-7. Epub 2019 Oct 21. Nat Microbiol. 2019. PMID: 31636419 Free PMC article.
64 results