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Comparison of phenotypic and transcriptomic effects of false-positive genotoxins, true genotoxins and non-genotoxins using HepG2 cells.
Magkoufopoulou C, Claessen SM, Jennen DG, Kleinjans JC, van Delft JH. Magkoufopoulou C, et al. Among authors: claessen sm. Mutagenesis. 2011 Sep;26(5):593-604. doi: 10.1093/mutage/ger021. Epub 2011 Jun 1. Mutagenesis. 2011. PMID: 21632981
The idiosyncratic drug-induced gene expression changes in HepG2 cells.
Jiang J, Mathijs K, Timmermans L, Claessen SM, Hecka A, Weusten J, Peters R, van Delft JH, Kleinjans JCS, Jennen DGJ, de Kok TM. Jiang J, et al. Among authors: claessen sm. Data Brief. 2017 Jul 29;14:462-468. doi: 10.1016/j.dib.2017.07.074. eCollection 2017 Oct. Data Brief. 2017. PMID: 28831409 Free PMC article.
Baseline and genotoxic compound induced gene expression profiles in HepG2 and HepaRG compared to primary human hepatocytes.
Jetten MJ, Kleinjans JC, Claessen SM, Chesné C, van Delft JH. Jetten MJ, et al. Among authors: claessen sm. Toxicol In Vitro. 2013 Oct;27(7):2031-40. doi: 10.1016/j.tiv.2013.07.010. Epub 2013 Jul 31. Toxicol In Vitro. 2013. PMID: 23911569
Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury.
Jiang J, Mathijs K, Timmermans L, Claessen SM, Hecka A, Weusten J, Peters R, van Delft JH, Kleinjans JCS, Jennen DGJ, de Kok TM. Jiang J, et al. Among authors: claessen sm. Toxicol Appl Pharmacol. 2017 Oct 1;332:100-108. doi: 10.1016/j.taap.2017.07.014. Epub 2017 Jul 18. Toxicol Appl Pharmacol. 2017. PMID: 28733206
Cell line-specific oxidative stress in cellular toxicity: A toxicogenomics-based comparison between liver and colon cell models.
Deferme L, Briedé JJ, Claessen SM, Cavill R, Kleinjans JC. Deferme L, et al. Among authors: claessen sm. Toxicol In Vitro. 2015 Aug;29(5):845-55. doi: 10.1016/j.tiv.2015.03.007. Epub 2015 Mar 21. Toxicol In Vitro. 2015. PMID: 25800948
Time series analysis of oxidative stress response patterns in HepG2: a toxicogenomics approach.
Deferme L, Briedé JJ, Claessen SM, Jennen DG, Cavill R, Kleinjans JC. Deferme L, et al. Among authors: claessen sm. Toxicology. 2013 Apr 5;306:24-34. doi: 10.1016/j.tox.2013.02.001. Epub 2013 Feb 11. Toxicology. 2013. PMID: 23410634
A transcriptomics-based in vitro assay for predicting chemical genotoxicity in vivo.
Magkoufopoulou C, Claessen SM, Tsamou M, Jennen DG, Kleinjans JC, van Delft JH. Magkoufopoulou C, et al. Among authors: claessen sm. Carcinogenesis. 2012 Jul;33(7):1421-9. doi: 10.1093/carcin/bgs182. Epub 2012 May 23. Carcinogenesis. 2012. PMID: 22623647
Data on novel DNA methylation changes induced by valproic acid in human hepatocytes.
Wolters J, van Breda S, Claessen S, de Kok T, Kleinjans J. Wolters J, et al. Data Brief. 2017 Nov 10;16:161-171. doi: 10.1016/j.dib.2017.11.031. eCollection 2018 Feb. Data Brief. 2017. PMID: 29201983 Free PMC article.
Novel candidate tumour suppressor gene loci on chromosomes 11q23-24 and 22q13 involved in human insulinoma tumourigenesis.
Jonkers YM, Claessen SM, Feuth T, van Kessel AG, Ramaekers FC, Veltman JA, Speel EJ. Jonkers YM, et al. Among authors: claessen sm. J Pathol. 2006 Dec;210(4):450-8. doi: 10.1002/path.2072. J Pathol. 2006. PMID: 17068744
Molecular parameters associated with insulinoma progression: chromosomal instability versus p53 and CK19 status.
Jonkers YM, Claessen SM, Veltman JA, Geurts van Kessel A, Dinjens WN, Skogseid B, Ramaekers FC, Speel EJ. Jonkers YM, et al. Among authors: claessen sm. Cytogenet Genome Res. 2006;115(3-4):289-97. doi: 10.1159/000095926. Cytogenet Genome Res. 2006. PMID: 17124412
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