Clair T - Search Results

1

Phospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression.

Im E, Motiejunaite R, Aranda J, Park EY, Federico L, Kim TI, Clair T, Stracke ML, Smyth S, Kazlauskas A. Im E, et al. Among authors: clair t. Mol Cell Biol. 2010 May;30(10):2401-10. doi: 10.1128/MCB.01275-09. Epub 2010 Mar 15. Mol Cell Biol. 2010. PMID: 20231358 Free PMC article.

2

L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin.

Clair T, Koh E, Ptaszynska M, Bandle RW, Liotta LA, Schiffmann E, Stracke ML. Clair T, et al. Lipids Health Dis. 2005 Feb 28;4:5. doi: 10.1186/1476-511X-4-5. Lipids Health Dis. 2005. PMID: 15737239 Free PMC article.

3

Novel point mutations attenuate autotaxin activity.

Koh E, Bandle RW, Roberts DD, Stracke ML, Clair T. Koh E, et al. Among authors: clair t. Lipids Health Dis. 2009 Feb 17;8:4. doi: 10.1186/1476-511X-8-4. Lipids Health Dis. 2009. PMID: 19222837 Free PMC article.

4

Site-directed mutations in the tumor-associated cytokine, autotaxin, eliminate nucleotide phosphodiesterase, lysophospholipase D, and motogenic activities.

Koh E, Clair T, Woodhouse EC, Schiffmann E, Liotta L, Stracke M. Koh E, et al. Among authors: clair t. Cancer Res. 2003 May 1;63(9):2042-5. Cancer Res. 2003. PMID: 12727817

5

Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate.

Clair T, Aoki J, Koh E, Bandle RW, Nam SW, Ptaszynska MM, Mills GB, Schiffmann E, Liotta LA, Stracke ML. Clair T, et al. Cancer Res. 2003 Sep 1;63(17):5446-53. Cancer Res. 2003. PMID: 14500380

6

Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells.

Nam SW, Clair T, Campo CK, Lee HY, Liotta LA, Stracke ML. Nam SW, et al. Among authors: clair t. Oncogene. 2000 Jan 13;19(2):241-7. doi: 10.1038/sj.onc.1203263. Oncogene. 2000. PMID: 10645002

7

Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor.

Nam SW, Clair T, Kim YS, McMarlin A, Schiffmann E, Liotta LA, Stracke ML. Nam SW, et al. Among authors: clair t. Cancer Res. 2001 Sep 15;61(18):6938-44. Cancer Res. 2001. PMID: 11559573

8

Autotaxin is an exoenzyme possessing 5'-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities.

Clair T, Lee HY, Liotta LA, Stracke ML. Clair T, et al. J Biol Chem. 1997 Jan 10;272(2):996-1001. doi: 10.1074/jbc.272.2.996. J Biol Chem. 1997. PMID: 8995394 Free article.

., and Liotta, L. (1992) J. Biol. Chem. 267, 2524-2529; Murata, J., Lee, H. Y., Clair, T., Krutsch, H. C., Arestad, A. A., Sobel, M. E., Liotta, L. ...Thr210 at the PDE active site of ATX is required for phosphorylation, 5'-nucleotide PDE, and motility-stimulating a …

., and Liotta, L. (1992) J. Biol. Chem. 267, 2524-2529; Murata, J., Lee, H. Y., Clair, T., Krutsch, H. C., Arestad, A. A., Sob …

9

Nucleotide binding to autotaxin: crosslinking of bound substrate followed by lysC digestion identifies two labeled peptides.

Clair T, Krutzsch HC, Liotta LA, Stracke ML. Clair T, et al. Biochem Biophys Res Commun. 1997 Jul 18;236(2):449-54. doi: 10.1006/bbrc.1997.6982. Biochem Biophys Res Commun. 1997. PMID: 9240459

10

Autotaxin, tumor motility-stimulating exophosphodiesterase.

Stracke ML, Clair T, Liotta LA. Stracke ML, et al. Among authors: clair t. Adv Enzyme Regul. 1997;37:135-44. doi: 10.1016/s0065-2571(96)00017-9. Adv Enzyme Regul. 1997. PMID: 9381968

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