Clampit JE - Search Results

1

Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes.

Gonzalez-Rodriguez A, Clampit JE, Escribano O, Benito M, Rondinone CM, Valverde AM. Gonzalez-Rodriguez A, et al. Among authors: clampit je. Endocrinology. 2007 Feb;148(2):594-608. doi: 10.1210/en.2006-0644. Epub 2006 Oct 26. Endocrinology. 2007. PMID: 17068137 Free article.

2

Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice.

Gum RJ, Gaede LL, Koterski SL, Heindel M, Clampit JE, Zinker BA, Trevillyan JM, Ulrich RG, Jirousek MR, Rondinone CM. Gum RJ, et al. Among authors: clampit je. Diabetes. 2003 Jan;52(1):21-8. doi: 10.2337/diabetes.52.1.21. Diabetes. 2003. PMID: 12502489

3

Reduction of protein-tyrosine phosphatase-1B increases insulin signaling in FAO hepatoma cells.

Clampit JE, Meuth JL, Smith HT, Reilly RM, Jirousek MR, Trevillyan JM, Rondinone CM. Clampit JE, et al. Biochem Biophys Res Commun. 2003 Jan 10;300(2):261-7. doi: 10.1016/s0006-291x(02)02839-5. Biochem Biophys Res Commun. 2003. PMID: 12504077

4

PTP1B antisense-treated mice show regulation of genes involved in lipogenesis in liver and fat.

Waring JF, Ciurlionis R, Clampit JE, Morgan S, Gum RJ, Jolly RA, Kroeger P, Frost L, Trevillyan J, Zinker BA, Jirousek M, Ulrich RG, Rondinone CM. Waring JF, et al. Among authors: clampit je. Mol Cell Endocrinol. 2003 May 30;203(1-2):155-68. doi: 10.1016/s0303-7207(03)00008-x. Mol Cell Endocrinol. 2003. PMID: 12782412

5

Protein tyrosine phosphatase 1B reduction regulates adiposity and expression of genes involved in lipogenesis.

Rondinone CM, Trevillyan JM, Clampit J, Gum RJ, Berg C, Kroeger P, Frost L, Zinker BA, Reilly R, Ulrich R, Butler M, Monia BP, Jirousek MR, Waring JF. Rondinone CM, et al. Diabetes. 2002 Aug;51(8):2405-11. doi: 10.2337/diabetes.51.8.2405. Diabetes. 2002. PMID: 12145151

6

Reduction of PTP1B induces differential expression of PI3-kinase (p85alpha) isoforms.

Rondinone CM, Clampit J, Gum RJ, Zinker BA, Jirousek MR, Trevillyan JM. Rondinone CM, et al. Biochem Biophys Res Commun. 2004 Oct 15;323(2):652-9. doi: 10.1016/j.bbrc.2004.08.138. Biochem Biophys Res Commun. 2004. PMID: 15369800

7

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice.

Zinker BA, Rondinone CM, Trevillyan JM, Gum RJ, Clampit JE, Waring JF, Xie N, Wilcox D, Jacobson P, Frost L, Kroeger PE, Reilly RM, Koterski S, Opgenorth TJ, Ulrich RG, Crosby S, Butler M, Murray SF, McKay RA, Bhanot S, Monia BP, Jirousek MR. Zinker BA, et al. Among authors: clampit je. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11357-62. doi: 10.1073/pnas.142298199. Epub 2002 Aug 8. Proc Natl Acad Sci U S A. 2002. PMID: 12169659 Free PMC article.

8

PKCtheta is a key player in the development of insulin resistance.

Haasch D, Berg C, Clampit JE, Pederson T, Frost L, Kroeger P, Rondinone CM. Haasch D, et al. Among authors: clampit je. Biochem Biophys Res Commun. 2006 May 5;343(2):361-8. doi: 10.1016/j.bbrc.2006.02.177. Epub 2006 Mar 9. Biochem Biophys Res Commun. 2006. PMID: 16545776

9

Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies.

Liu M, Wang S, Clampit JE, Gum RJ, Haasch DL, Rondinone CM, Trevillyan JM, Abad-Zapatero C, Fry EH, Sham HL, Liu G. Liu M, et al. Among authors: clampit je. Bioorg Med Chem Lett. 2007 Feb 1;17(3):668-72. doi: 10.1016/j.bmcl.2006.10.093. Epub 2006 Nov 2. Bioorg Med Chem Lett. 2007. PMID: 17107797

10

Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity.

Szczepankiewicz BG, Kosogof C, Nelson LT, Liu G, Liu B, Zhao H, Serby MD, Xin Z, Liu M, Gum RJ, Haasch DL, Wang S, Clampit JE, Johnson EF, Lubben TH, Stashko MA, Olejniczak ET, Sun C, Dorwin SA, Haskins K, Abad-Zapatero C, Fry EH, Hutchins CW, Sham HL, Rondinone CM, Trevillyan JM. Szczepankiewicz BG, et al. Among authors: clampit je. J Med Chem. 2006 Jun 15;49(12):3563-80. doi: 10.1021/jm060199b. J Med Chem. 2006. PMID: 16759099

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