Clapp LH - Search Results

1

Role of prostanoid IP and EP receptors in mediating vasorelaxant responses to PGI2 analogues in rat tail artery: Evidence for Gi/o modulation via EP3 receptors.

Orie NN, Clapp LH. Orie NN, et al. Among authors: clapp lh. Eur J Pharmacol. 2011 Mar 11;654(3):258-65. doi: 10.1016/j.ejphar.2010.12.005. Epub 2010 Dec 24. Eur J Pharmacol. 2011. PMID: 21185823

2

Prostanoid EP₂ Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells.

Patel JA, Shen L, Hall SM, Benyahia C, Norel X, McAnulty RJ, Moledina S, Silverstein AM, Whittle BJ, Clapp LH. Patel JA, et al. Among authors: clapp lh. Int J Mol Sci. 2018 Aug 12;19(8):2372. doi: 10.3390/ijms19082372. Int J Mol Sci. 2018. PMID: 30103548 Free PMC article. Clinical Trial.

3

Pharmacology of the single isomer, esuberaprost (beraprost-314d) on pulmonary vascular tone, IP receptors and human smooth muscle proliferation in pulmonary hypertension.

Shen L, Patel JA, Norel X, Moledina S, Whittle BJ, von Kessler K, Sista P, Clapp LH. Shen L, et al. Among authors: clapp lh. Biochem Pharmacol. 2019 Aug;166:242-252. doi: 10.1016/j.bcp.2019.05.026. Epub 2019 May 31. Biochem Pharmacol. 2019. PMID: 31158340

4

Inotropic Effects of Prostacyclins on the Right Ventricle Are Abolished in Isolated Rat Hearts With Right-Ventricular Hypertrophy and Failure.

Holmboe S, Andersen A, Johnsen J, Nielsen JM, Nørregaard R, Bøtker HE, Clapp LH, Nielsen-Kudsk JE. Holmboe S, et al. Among authors: clapp lh. J Cardiovasc Pharmacol. 2017 Jan;69(1):1-12. doi: 10.1097/FJC.0000000000000435. J Cardiovasc Pharmacol. 2017. PMID: 27652910

5

Ex vivo relaxations of pulmonary arteries induced by prostacyclin mimetics are highly dependent of the precontractile agents.

Benyahia C, Ozen G, Orie N, Ledwozyw A, Louedec L, Li F, Senbel AM, Silverstein A, Danel C, Longrois D, Clapp LH, Norel X, Topal G. Benyahia C, et al. Among authors: clapp lh. Prostaglandins Other Lipid Mediat. 2015 Sep;121(Pt A):46-52. doi: 10.1016/j.prostaglandins.2015.09.002. Epub 2015 Sep 8. Prostaglandins Other Lipid Mediat. 2015. PMID: 26362969

6

Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: treprostinil is a potent DP1 and EP2 agonist.

Whittle BJ, Silverstein AM, Mottola DM, Clapp LH. Whittle BJ, et al. Among authors: clapp lh. Biochem Pharmacol. 2012 Jul 1;84(1):68-75. doi: 10.1016/j.bcp.2012.03.012. Epub 2012 Mar 27. Biochem Pharmacol. 2012. PMID: 22480736

7

The pore-forming subunit of the K(ATP) channel is an important molecular target for LPS-induced vascular hyporeactivity in vitro.

O'Brien AJ, Thakur G, Buckley JF, Singer M, Clapp LH. O'Brien AJ, et al. Among authors: clapp lh. Br J Pharmacol. 2005 Feb;144(3):367-75. doi: 10.1038/sj.bjp.0706065. Br J Pharmacol. 2005. PMID: 15655519 Free PMC article.

8

Evidence that inward rectifier K+ channels mediate relaxation by the PGI2 receptor agonist cicaprost via a cyclic AMP-independent mechanism.

Orie NN, Fry CH, Clapp LH. Orie NN, et al. Among authors: clapp lh. Cardiovasc Res. 2006 Jan;69(1):107-15. doi: 10.1016/j.cardiores.2005.08.004. Epub 2005 Sep 23. Cardiovasc Res. 2006. PMID: 16183044

9

Different molecular sites of action for the KATP channel inhibitors, PNU-99963 and PNU-37883A.

Cui Y, Tinker A, Clapp LH. Cui Y, et al. Among authors: clapp lh. Br J Pharmacol. 2003 May;139(1):122-8. doi: 10.1038/sj.bjp.0705228. Br J Pharmacol. 2003. PMID: 12746230 Free PMC article.

10

The molecular site of action of K(ATP) channel inhibitors determines their ability to inhibit iNOS-mediated relaxation in rat aorta.

Wilson AJ, Clapp LH. Wilson AJ, et al. Among authors: clapp lh. Cardiovasc Res. 2002 Oct;56(1):154-63. doi: 10.1016/s0008-6363(02)00504-7. Cardiovasc Res. 2002. PMID: 12237176

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