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New natural product families from an environmental DNA (eDNA) gene cluster.
Brady SF, Chao CJ, Clardy J. Brady SF, et al. Among authors: clardy j. J Am Chem Soc. 2002 Aug 28;124(34):9968-9. doi: 10.1021/ja0268985. J Am Chem Soc. 2002. PMID: 12188643
Minimum Information about a Biosynthetic Gene cluster.
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO. Medema MH, et al. Among authors: clardy j. Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. Nat Chem Biol. 2015. PMID: 26284661 Free PMC article. No abstract available.
Synthesis of long-chain fatty acid enol esters isolated from an environmental DNA clone.
Brady SF, Clardy J. Brady SF, et al. Among authors: clardy j. Org Lett. 2003 Jan 23;5(2):121-4. doi: 10.1021/ol0267681. Org Lett. 2003. PMID: 12529120
The biosynthetic gene cluster of Pantocin a provides insights into biosynthesis and a tool for screening.
Jin M, Wright SA, Beer SV, Clardy J. Jin M, et al. Among authors: clardy j. Angew Chem Int Ed Engl. 2003 Jun 30;42(25):2902-5. doi: 10.1002/anie.200351054. Angew Chem Int Ed Engl. 2003. PMID: 12833354 No abstract available.
Structural and functional analysis of pantocin A: an antibiotic from Pantoea agglomerans discovered by heterologous expression of cloned genes.
Jin M, Liu L, Wright SA, Beer SV, Clardy J. Jin M, et al. Among authors: clardy j. Angew Chem Int Ed Engl. 2003 Jun 30;42(25):2898-901. doi: 10.1002/anie.200351053. Angew Chem Int Ed Engl. 2003. PMID: 12833353 No abstract available.
N-acyl derivatives of arginine and tryptophan isolated from environmental DNA expressed in Escherichia coli.
Brady SF, Clardy J. Brady SF, et al. Among authors: clardy j. Org Lett. 2005 Aug 18;7(17):3613-6. doi: 10.1021/ol0509585. Org Lett. 2005. PMID: 16092832
Synthesis and biological evaluation of analogues of the antibiotic pantocin B.
Sutton AE, Clardy J. Sutton AE, et al. Among authors: clardy j. J Am Chem Soc. 2001 Oct 17;123(41):9935-46. doi: 10.1021/ja003770j. J Am Chem Soc. 2001. PMID: 11592872
9,11-Secogorgost-5-en-9-one-3 beta,11-diol, a marine steroid from the sea whip Pseudopterogorgia hummelinkii.
Schultz LW, Clardy J, Lessinger L. Schultz LW, et al. Among authors: clardy j. Acta Crystallogr C. 1995 Mar 15;51 ( Pt 3):415-9. doi: 10.1107/s010827019400452x. Acta Crystallogr C. 1995. PMID: 7734087
The guanacastepenes: a highly diverse family of secondary metabolites produced by an endophytic fungus.
Brady SF, Bondi SM, Clardy J. Brady SF, et al. Among authors: clardy j. J Am Chem Soc. 2001 Oct 10;123(40):9900-1. doi: 10.1021/ja016176y. J Am Chem Soc. 2001. PMID: 11583556 No abstract available.
Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA.
Brady SF, Chao CJ, Handelsman J, Clardy J. Brady SF, et al. Among authors: clardy j. Org Lett. 2001 Jun 28;3(13):1981-4. doi: 10.1021/ol015949k. Org Lett. 2001. PMID: 11418029
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