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Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities.
Carling D, Clarke PR, Zammit VA, Hardie DG. Carling D, et al. Among authors: clarke pr. Eur J Biochem. 1989 Dec 8;186(1-2):129-36. doi: 10.1111/j.1432-1033.1989.tb15186.x. Eur J Biochem. 1989. PMID: 2598924
Calmodulin-dependent multiprotein kinase and protein kinase C phosphorylate the same site on HMG-CoA reductase as the AMP-activated protein kinase.
Clarke PR, Hardie DG. Clarke PR, et al. FEBS Lett. 1990 Aug 20;269(1):213-7. doi: 10.1016/0014-5793(90)81157-j. FEBS Lett. 1990. PMID: 2387404
Regulation of HMG-CoA reductase: identification of the site phosphorylated by the AMP-activated protein kinase in vitro and in intact rat liver.
Clarke PR, Hardie DG. Clarke PR, et al. EMBO J. 1990 Aug;9(8):2439-46. EMBO J. 1990. PMID: 2369897 Free PMC article.
Evidence for a protein kinase cascade in higher plants. 3-Hydroxy-3-methylglutaryl-CoA reductase kinase.
Mackintosh RW, Davies SP, Clarke PR, Weekes J, Gillespie JG, Gibb BJ, Hardie DG. Mackintosh RW, et al. Among authors: clarke pr. Eur J Biochem. 1992 Nov 1;209(3):923-31. doi: 10.1111/j.1432-1033.1992.tb17364.x. Eur J Biochem. 1992. PMID: 1358611
Adenosine monophosphate-activated protein kinase: hydroxymethylglutaryl-CoA reductase kinase.
Carling D, Clarke PR, Hardie DG. Carling D, et al. Among authors: clarke pr. Methods Enzymol. 1991;200:362-71. doi: 10.1016/0076-6879(91)00153-n. Methods Enzymol. 1991. PMID: 1683469 No abstract available.
Okadaic acid-sensitive protein phosphatases dephosphorylate MARCKS, a major protein kinase C substrate.
Clarke PR, Siddhanti SR, Cohen P, Blackshear PJ. Clarke PR, et al. FEBS Lett. 1993 Dec 20;336(1):37-42. doi: 10.1016/0014-5793(93)81604-x. FEBS Lett. 1993. PMID: 8262213
Cyclin-dependent kinases. CAK-handed kinase activation.
Clarke PR. Clarke PR. Curr Biol. 1995 Jan 1;5(1):40-2. doi: 10.1016/s0960-9822(95)00013-3. Curr Biol. 1995. PMID: 7697347 Review.
Phosphorylation of importin-α1 by CDK1-cyclin B1 controls mitotic spindle assembly.
Guo L, Mohd KS, Ren H, Xin G, Jiang Q, Clarke PR, Zhang C. Guo L, et al. Among authors: clarke pr. J Cell Sci. 2019 Sep 23;132(18):jcs232314. doi: 10.1242/jcs.232314. J Cell Sci. 2019. PMID: 31434716 Free PMC article.
Timed degradation of Mcl-1 controls mitotic cell death.
Clarke PR, Allan LA, Skowyra A. Clarke PR, et al. Mol Cell Oncol. 2018 Oct 11;5(6):e1516450. doi: 10.1080/23723556.2018.1516450. eCollection 2018. Mol Cell Oncol. 2018. PMID: 30525093 Free PMC article.
Atypical APC/C-dependent degradation of Mcl-1 provides an apoptotic timer during mitotic arrest.
Allan LA, Skowyra A, Rogers KI, Zeller D, Clarke PR. Allan LA, et al. Among authors: clarke pr. EMBO J. 2018 Sep 3;37(17):e96831. doi: 10.15252/embj.201796831. Epub 2018 Jul 9. EMBO J. 2018. PMID: 29987118 Free PMC article.
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