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23 results
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Intracellular sensors of extracellular bacteria.
Clarke TB, Weiser JN. Clarke TB, et al. Immunol Rev. 2011 Sep;243(1):9-25. doi: 10.1111/j.1600-065X.2011.01039.x. Immunol Rev. 2011. PMID: 21884164 Review.
Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis.
Hergott CB, Roche AM, Tamashiro E, Clarke TB, Bailey AG, Laughlin A, Bushman FD, Weiser JN. Hergott CB, et al. Among authors: clarke tb. Blood. 2016 May 19;127(20):2460-71. doi: 10.1182/blood-2015-10-675173. Epub 2016 Mar 17. Blood. 2016. PMID: 26989200 Free PMC article.
Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity.
Clarke TB, Davis KM, Lysenko ES, Zhou AY, Yu Y, Weiser JN. Clarke TB, et al. Nat Med. 2010 Feb;16(2):228-31. doi: 10.1038/nm.2087. Epub 2010 Jan 17. Nat Med. 2010. PMID: 20081863 Free PMC article.
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing.
Lysenko ES, Clarke TB, Shchepetov M, Ratner AJ, Roper DI, Dowson CG, Weiser JN. Lysenko ES, et al. Among authors: clarke tb. PLoS Pathog. 2007 Aug 24;3(8):e118. doi: 10.1371/journal.ppat.0030118. PLoS Pathog. 2007. PMID: 17722978 Free PMC article.
Invasive bacterial pathogens exploit TLR-mediated downregulation of tight junction components to facilitate translocation across the epithelium.
Clarke TB, Francella N, Huegel A, Weiser JN. Clarke TB, et al. Cell Host Microbe. 2011 May 19;9(5):404-14. doi: 10.1016/j.chom.2011.04.012. Cell Host Microbe. 2011. PMID: 21575911 Free PMC article.
Cellular effectors mediating Th17-dependent clearance of pneumococcal colonization in mice.
Zhang Z, Clarke TB, Weiser JN. Zhang Z, et al. Among authors: clarke tb. J Clin Invest. 2009 Jul;119(7):1899-909. doi: 10.1172/JCI36731. Epub 2009 Jun 8. J Clin Invest. 2009. PMID: 19509469 Free PMC article.
The microbiota protects against respiratory infection via GM-CSF signaling.
Brown RL, Sequeira RP, Clarke TB. Brown RL, et al. Among authors: clarke tb. Nat Commun. 2017 Nov 15;8(1):1512. doi: 10.1038/s41467-017-01803-x. Nat Commun. 2017. PMID: 29142211 Free PMC article.
Inhibiting Growth of Clostridioides difficile by Restoring Valerate, Produced by the Intestinal Microbiota.
McDonald JAK, Mullish BH, Pechlivanis A, Liu Z, Brignardello J, Kao D, Holmes E, Li JV, Clarke TB, Thursz MR, Marchesi JR. McDonald JAK, et al. Among authors: clarke tb. Gastroenterology. 2018 Nov;155(5):1495-1507.e15. doi: 10.1053/j.gastro.2018.07.014. Epub 2018 Jul 17. Gastroenterology. 2018. PMID: 30025704 Free PMC article.
The regulation of host defences to infection by the microbiota.
Brown RL, Clarke TB. Brown RL, et al. Among authors: clarke tb. Immunology. 2017 Jan;150(1):1-6. doi: 10.1111/imm.12634. Epub 2016 Aug 9. Immunology. 2017. PMID: 27311879 Free PMC article. Review.
Early innate immunity to bacterial infection in the lung is regulated systemically by the commensal microbiota via nod-like receptor ligands.
Clarke TB. Clarke TB. Infect Immun. 2014 Nov;82(11):4596-606. doi: 10.1128/IAI.02212-14. Epub 2014 Aug 18. Infect Immun. 2014. PMID: 25135683 Free PMC article.
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