Clarkin KC - Search Results

1

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

Linke SP, Clarkin KC, Di Leonardo A, Tsou A, Wahl GM. Linke SP, et al. Among authors: clarkin kc. Genes Dev. 1996 Apr 15;10(8):934-47. doi: 10.1101/gad.10.8.934. Genes Dev. 1996. PMID: 8608941 Free article.

2

Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest.

Huang LC, Clarkin KC, Wahl GM. Huang LC, et al. Among authors: clarkin kc. Proc Natl Acad Sci U S A. 1996 May 14;93(10):4827-32. doi: 10.1073/pnas.93.10.4827. Proc Natl Acad Sci U S A. 1996. PMID: 8643488 Free PMC article.

3

p53-dependent cell cycle arrests are preserved in DNA-activated protein kinase-deficient mouse fibroblasts.

Huang LC, Clarkin KC, Wahl GM. Huang LC, et al. Among authors: clarkin kc. Cancer Res. 1996 Jul 1;56(13):2940-4. Cancer Res. 1996. PMID: 8674045

4

p53 mediates permanent arrest over multiple cell cycles in response to gamma-irradiation.

Linke SP, Clarkin KC, Wahl GM. Linke SP, et al. Among authors: clarkin kc. Cancer Res. 1997 Mar 15;57(6):1171-9. Cancer Res. 1997. PMID: 9067289

5

p53-mediated accumulation of hypophosphorylated pRb after the G1 restriction point fails to halt cell cycle progression.

Linke SP, Harris MP, Neugebauer SE, Clarkin KC, Shepard HM, Maneval DC, Wahl GM. Linke SP, et al. Among authors: clarkin kc. Oncogene. 1997 Jul 17;15(3):337-45. doi: 10.1038/sj.onc.1201200. Oncogene. 1997. PMID: 9233768

6

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.

Di Leonardo A, Linke SP, Clarkin K, Wahl GM. Di Leonardo A, et al. Genes Dev. 1994 Nov 1;8(21):2540-51. doi: 10.1101/gad.8.21.2540. Genes Dev. 1994. PMID: 7958916 Free article.

7

Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant alpha4beta2 nicotinic acetylcholine receptor potentiators.

Albrecht BK, Berry V, Boezio AA, Cao L, Clarkin K, Guo W, Harmange JC, Hierl M, Huang L, Janosky B, Knop J, Malmberg A, McDermott JS, Nguyen HQ, Springer SK, Waldon D, Woodin K, McDonough SI. Albrecht BK, et al. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5209-12. doi: 10.1016/j.bmcl.2008.08.080. Epub 2008 Aug 28. Bioorg Med Chem Lett. 2008. PMID: 18789861

8

Activation of Lyt-2 associated with distant upstream insertion of an SL3-3 provirus.

Anson DS, Clarkin K, Hyman R. Anson DS, et al. Immunogenetics. 1992;36(1):3-14. doi: 10.1007/BF00209286. Immunogenetics. 1992. PMID: 1587551

9

Sequential activation and loss of the pre-B cell Thy-1 gene in T-cell X pre-B cell somatic hybrids.

Hyman R, Clarkin K. Hyman R, et al. Immunogenetics. 1988;27(5):313-21. doi: 10.1007/BF00395126. Immunogenetics. 1988. PMID: 2895732

10

Synthesis and activity of substituted carbamates as potentiators of the alpha4beta2 nicotinic acetylcholine receptor.

Springer SK, Woodin KS, Berry V, Boezio AA, Cao L, Clarkin K, Harmange JC, Hierl M, Knop J, Malmberg AB, McDermott JS, Nguyen HQ, Waldon D, Albrecht BK, McDonough SI. Springer SK, et al. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5643-7. doi: 10.1016/j.bmcl.2008.08.092. Epub 2008 Aug 29. Bioorg Med Chem Lett. 2008. PMID: 18805006

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