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In vitro antiplasmodial activity of abietane and totarane diterpenes isolated from Harpagophytum procumbens (devil's claw).
Clarkson C, Campbell WE, Smith P. Clarkson C, et al. Planta Med. 2003 Aug;69(8):720-4. doi: 10.1055/s-2003-42778. Planta Med. 2003. PMID: 14531022
5alpha-cardenolides from Kanahia laniflora inhibit ionotropic acetylcholine receptors.
Clarkson C, Mellor IR, Lambert M, Jaroszewski JW. Clarkson C, et al. Planta Med. 2006 Dec;72(15):1418-20. doi: 10.1055/s-2006-951704. Epub 2006 Oct 20. Planta Med. 2006. PMID: 17054051
Identification of major and minor constituents of Harpagophytum procumbens (Devil's claw) using HPLC-SPE-NMR and HPLC-ESIMS/APCIMS.
Clarkson C, Staerk D, Hansen SH, Smith PJ, Jaroszewski JW. Clarkson C, et al. J Nat Prod. 2006 Sep;69(9):1280-8. doi: 10.1021/np0601612. J Nat Prod. 2006. PMID: 16989520
Discovering new natural products directly from crude extracts by HPLC-SPE-NMR: chinane diterpenes in Harpagophytum procumbens.
Clarkson C, Staerk D, Hansen SH, Smith PJ, Jaroszewski JW. Clarkson C, et al. J Nat Prod. 2006 Apr;69(4):527-30. doi: 10.1021/np050504g. J Nat Prod. 2006. PMID: 16643019
Design, synthesis and anti-plasmodial evaluation in vitro of new 4-aminoquinoline isatin derivatives.
Chiyanzu I, Clarkson C, Smith PJ, Lehman J, Gut J, Rosenthal PJ, Chibale K. Chiyanzu I, et al. Among authors: clarkson c. Bioorg Med Chem. 2005 May 2;13(9):3249-61. doi: 10.1016/j.bmc.2005.02.037. Bioorg Med Chem. 2005. PMID: 15809160
In vitro antimalarial activity of a series of cationic 2,2'-bipyridyl- and 1,10-phenanthrolineplatinum(II) benzoylthiourea complexes.
Egan TJ, Koch KR, Swan PL, Clarkson C, Van Schalkwyk DA, Smith PJ. Egan TJ, et al. Among authors: clarkson c. J Med Chem. 2004 May 20;47(11):2926-34. doi: 10.1021/jm031132g. J Med Chem. 2004. PMID: 15139771
In vitro antiplasmodial activity of medicinal plants native to or naturalised in South Africa.
Clarkson C, Maharaj VJ, Crouch NR, Grace OM, Pillay P, Matsabisa MG, Bhagwandin N, Smith PJ, Folb PI. Clarkson C, et al. J Ethnopharmacol. 2004 Jun;92(2-3):177-91. doi: 10.1016/j.jep.2004.02.011. J Ethnopharmacol. 2004. PMID: 15137999
Synthesis of totarol amino alcohol derivatives and their antiplasmodial activity and cytotoxicity.
Clarkson C, Musonda CC, Chibale K, Campbell WE, Smith P. Clarkson C, et al. Bioorg Med Chem. 2003 Oct 1;11(20):4417-22. doi: 10.1016/s0968-0896(03)00491-7. Bioorg Med Chem. 2003. PMID: 13129578
HPLC-SPE-NMR characterization of sesquiterpenes in an antimycobacterial fraction from Warburgia salutaris.
Clarkson C, Madikane EV, Hansen SH, Smith PJ, Jaroszewski JW. Clarkson C, et al. Planta Med. 2007 Jun;73(6):578-84. doi: 10.1055/s-2007-967187. Epub 2007 May 7. Planta Med. 2007. PMID: 17486536
Evaluation of on-line solid-phase extraction parameters for hyphenated, high-performance liquid chromatography-solid-phase extraction-nuclear magnetic resonance applications.
Clarkson C, Sibum M, Mensen R, Jaroszewski JW. Clarkson C, et al. J Chromatogr A. 2007 Sep 21;1165(1-2):1-9. doi: 10.1016/j.chroma.2007.07.016. Epub 2007 Jul 13. J Chromatogr A. 2007. PMID: 17709113
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