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Co-expression of truncated and full-length tau induces severe neurotoxicity.
Ozcelik S, Sprenger F, Skachokova Z, Fraser G, Abramowski D, Clavaguera F, Probst A, Frank S, Müller M, Staufenbiel M, Goedert M, Tolnay M, Winkler DT. Ozcelik S, et al. Among authors: clavaguera f. Mol Psychiatry. 2016 Dec;21(12):1790-1798. doi: 10.1038/mp.2015.228. Epub 2016 Feb 2. Mol Psychiatry. 2016. PMID: 26830137 Free PMC article.
"Prion-like" templated misfolding in tauopathies.
Clavaguera F, Lavenir I, Falcon B, Frank S, Goedert M, Tolnay M. Clavaguera F, et al. Brain Pathol. 2013 May;23(3):342-9. doi: 10.1111/bpa.12044. Brain Pathol. 2013. PMID: 23587140 Free PMC article. Review.
The Prion-Like Behavior of Assembled Tau in Transgenic Mice.
Clavaguera F, Tolnay M, Goedert M. Clavaguera F, et al. Cold Spring Harb Perspect Med. 2017 Oct 3;7(10):a024372. doi: 10.1101/cshperspect.a024372. Cold Spring Harb Perspect Med. 2017. PMID: 27940600 Free PMC article. Review.
Brain homogenates from human tauopathies induce tau inclusions in mouse brain.
Clavaguera F, Akatsu H, Fraser G, Crowther RA, Frank S, Hench J, Probst A, Winkler DT, Reichwald J, Staufenbiel M, Ghetti B, Goedert M, Tolnay M. Clavaguera F, et al. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9535-40. doi: 10.1073/pnas.1301175110. Epub 2013 May 20. Proc Natl Acad Sci U S A. 2013. PMID: 23690619 Free PMC article.
Transmission and spreading of tauopathy in transgenic mouse brain.
Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, Jucker M, Goedert M, Tolnay M. Clavaguera F, et al. Nat Cell Biol. 2009 Jul;11(7):909-13. doi: 10.1038/ncb1901. Epub 2009 Jun 7. Nat Cell Biol. 2009. PMID: 19503072 Free PMC article.
A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity.
Ahmed Z, Cooper J, Murray TK, Garn K, McNaughton E, Clarke H, Parhizkar S, Ward MA, Cavallini A, Jackson S, Bose S, Clavaguera F, Tolnay M, Lavenir I, Goedert M, Hutton ML, O'Neill MJ. Ahmed Z, et al. Among authors: clavaguera f. Acta Neuropathol. 2014 May;127(5):667-83. doi: 10.1007/s00401-014-1254-6. Epub 2014 Feb 16. Acta Neuropathol. 2014. PMID: 24531916 Free PMC article.
23 results