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The cytisine derivatives, CC4 and CC26, reduce nicotine-induced conditioned place preference in zebrafish by acting on heteromeric neuronal nicotinic acetylcholine receptors.
Ponzoni L, Braida D, Pucci L, Andrea D, Fasoli F, Manfredi I, Papke RL, Stokes C, Cannazza G, Clementi F, Gotti C, Sala M. Ponzoni L, et al. Among authors: clementi f. Psychopharmacology (Berl). 2014 Dec;231(24):4681-93. doi: 10.1007/s00213-014-3619-x. Epub 2014 May 27. Psychopharmacology (Berl). 2014. PMID: 24862365
Nicotinic acetylcholine receptors in the mesolimbic pathway: primary role of ventral tegmental area alpha6beta2* receptors in mediating systemic nicotine effects on dopamine release, locomotion, and reinforcement.
Gotti C, Guiducci S, Tedesco V, Corbioli S, Zanetti L, Moretti M, Zanardi A, Rimondini R, Mugnaini M, Clementi F, Chiamulera C, Zoli M. Gotti C, et al. Among authors: clementi f. J Neurosci. 2010 Apr 14;30(15):5311-25. doi: 10.1523/JNEUROSCI.5095-09.2010. J Neurosci. 2010. PMID: 20392953 Free PMC article.
Adolescent nicotine exposure transiently increases high-affinity nicotinic receptors and modulates inhibitory synaptic transmission in rat medial prefrontal cortex.
Counotte DS, Goriounova NA, Moretti M, Smoluch MT, Irth H, Clementi F, Schoffelmeer AN, Mansvelder HD, Smit AB, Gotti C, Spijker S. Counotte DS, et al. Among authors: clementi f. FASEB J. 2012 May;26(5):1810-20. doi: 10.1096/fj.11-198994. Epub 2012 Feb 3. FASEB J. 2012. PMID: 22308197 Free PMC article.
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