Clevers H - Search Results

1

The cancer stem cell: premises, promises and challenges.

Clevers H. Clevers H. Nat Med. 2011 Mar;17(3):313-9. doi: 10.1038/nm.2304. Nat Med. 2011. PMID: 21386835 Review.

2

Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4.

Schilham MW, Oosterwegel MA, Moerer P, Ya J, de Boer PA, van de Wetering M, Verbeek S, Lamers WH, Kruisbeek AM, Cumano A, Clevers H. Schilham MW, et al. Among authors: clevers h. Nature. 1996 Apr 25;380(6576):711-4. doi: 10.1038/380711a0. Nature. 1996. PMID: 8614465

3

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4.

Korinek V, Barker N, Moerer P, van Donselaar E, Huls G, Peters PJ, Clevers H. Korinek V, et al. Among authors: clevers h. Nat Genet. 1998 Aug;19(4):379-83. doi: 10.1038/1270. Nat Genet. 1998. PMID: 9697701

4

Wnt, stem cells and cancer in the intestine.

Pinto D, Clevers H. Pinto D, et al. Among authors: clevers h. Biol Cell. 2005 Mar;97(3):185-96. doi: 10.1042/BC20040094. Biol Cell. 2005. PMID: 15715524 Review.

5

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.

van Es JH, van Gijn ME, Riccio O, van den Born M, Vooijs M, Begthel H, Cozijnsen M, Robine S, Winton DJ, Radtke F, Clevers H. van Es JH, et al. Among authors: clevers h. Nature. 2005 Jun 16;435(7044):959-63. doi: 10.1038/nature03659. Nature. 2005. PMID: 15959515

6

EphB receptor activity suppresses colorectal cancer progression.

Batlle E, Bacani J, Begthel H, Jonkheer S, Gregorieff A, van de Born M, Malats N, Sancho E, Boon E, Pawson T, Gallinger S, Pals S, Clevers H. Batlle E, et al. Among authors: clevers h. Nature. 2005 Jun 23;435(7045):1126-30. doi: 10.1038/nature03626. Nature. 2005. PMID: 15973414

7

Identification of stem cells in small intestine and colon by marker gene Lgr5.

Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H. Barker N, et al. Among authors: clevers h. Nature. 2007 Oct 25;449(7165):1003-7. doi: 10.1038/nature06196. Epub 2007 Oct 14. Nature. 2007. PMID: 17934449

8

The intestinal stem cell.

Barker N, van de Wetering M, Clevers H. Barker N, et al. Among authors: clevers h. Genes Dev. 2008 Jul 15;22(14):1856-64. doi: 10.1101/gad.1674008. Genes Dev. 2008. PMID: 18628392 Free PMC article. Review.

9

Crypt stem cells as the cells-of-origin of intestinal cancer.

Barker N, Ridgway RA, van Es JH, van de Wetering M, Begthel H, van den Born M, Danenberg E, Clarke AR, Sansom OJ, Clevers H. Barker N, et al. Among authors: clevers h. Nature. 2009 Jan 29;457(7229):608-11. doi: 10.1038/nature07602. Epub 2008 Dec 17. Nature. 2009. PMID: 19092804

10

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

Sato T, Vries RG, Snippert HJ, van de Wetering M, Barker N, Stange DE, van Es JH, Abo A, Kujala P, Peters PJ, Clevers H. Sato T, et al. Among authors: clevers h. Nature. 2009 May 14;459(7244):262-5. doi: 10.1038/nature07935. Epub 2009 Mar 29. Nature. 2009. PMID: 19329995

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