Clevers H - Search Results

1

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.

Flanagan DJ, Pentinmikko N, Luopajärvi K, Willis NJ, Gilroy K, Raven AP, Mcgarry L, Englund JI, Webb AT, Scharaw S, Nasreddin N, Hodder MC, Ridgway RA, Minnee E, Sphyris N, Gilchrist E, Najumudeen AK, Romagnolo B, Perret C, Williams AC, Clevers H, Nummela P, Lähde M, Alitalo K, Hietakangas V, Hedley A, Clark W, Nixon C, Kirschner K, Jones EY, Ristimäki A, Leedham SJ, Fish PV, Vincent JP, Katajisto P, Sansom OJ. Flanagan DJ, et al. Among authors: clevers h. Nature. 2021 Jun;594(7863):430-435. doi: 10.1038/s41586-021-03525-z. Epub 2021 Jun 2. Nature. 2021. PMID: 34079124 Free PMC article.

2

An HMG-box-containing T-cell factor required for thymocyte differentiation.

Verbeek S, Izon D, Hofhuis F, Robanus-Maandag E, te Riele H, van de Wetering M, Oosterwegel M, Wilson A, MacDonald HR, Clevers H. Verbeek S, et al. Among authors: clevers h. Nature. 1995 Mar 2;374(6517):70-4. doi: 10.1038/374070a0. Nature. 1995. PMID: 7870176

3

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4.

Korinek V, Barker N, Moerer P, van Donselaar E, Huls G, Peters PJ, Clevers H. Korinek V, et al. Among authors: clevers h. Nat Genet. 1998 Aug;19(4):379-83. doi: 10.1038/1270. Nat Genet. 1998. PMID: 9697701

4

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis.

Zhang Z, Hartmann H, Do VM, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Sommer B, van de Wetering M, Clevers H, Saftig P, De Strooper B, He X, Yankner BA. Zhang Z, et al. Among authors: clevers h. Nature. 1998 Oct 15;395(6703):698-702. doi: 10.1038/27208. Nature. 1998. PMID: 9790190

5

Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway.

Wielenga VJ, Smits R, Korinek V, Smit L, Kielman M, Fodde R, Clevers H, Pals ST. Wielenga VJ, et al. Among authors: clevers h. Am J Pathol. 1999 Feb;154(2):515-23. doi: 10.1016/S0002-9440(10)65297-2. Am J Pathol. 1999. PMID: 10027409 Free PMC article.

6

Mutations in the APC tumour suppressor gene cause chromosomal instability.

Fodde R, Kuipers J, Rosenberg C, Smits R, Kielman M, Gaspar C, van Es JH, Breukel C, Wiegant J, Giles RH, Clevers H. Fodde R, et al. Among authors: clevers h. Nat Cell Biol. 2001 Apr;3(4):433-8. doi: 10.1038/35070129. Nat Cell Biol. 2001. PMID: 11283620

7

APC, signal transduction and genetic instability in colorectal cancer.

Fodde R, Smits R, Clevers H. Fodde R, et al. Among authors: clevers h. Nat Rev Cancer. 2001 Oct;1(1):55-67. doi: 10.1038/35094067. Nat Rev Cancer. 2001. PMID: 11900252 Review.

8

Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency.

Gallagher RC, Hay T, Meniel V, Naughton C, Anderson TJ, Shibata H, Ito M, Clevers H, Noda T, Sansom OJ, Mason JO, Clarke AR. Gallagher RC, et al. Among authors: clevers h. Oncogene. 2002 Sep 19;21(42):6446-57. doi: 10.1038/sj.onc.1205892. Oncogene. 2002. PMID: 12226748

9

The Wnt/beta-catenin pathway regulates cardiac valve formation.

Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H. Hurlstone AF, et al. Among authors: clevers h. Nature. 2003 Oct 9;425(6958):633-7. doi: 10.1038/nature02028. Nature. 2003. PMID: 14534590 Free article.

10

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration.

Sansom OJ, Reed KR, Hayes AJ, Ireland H, Brinkmann H, Newton IP, Batlle E, Simon-Assmann P, Clevers H, Nathke IS, Clarke AR, Winton DJ. Sansom OJ, et al. Among authors: clevers h. Genes Dev. 2004 Jun 15;18(12):1385-90. doi: 10.1101/gad.287404. Genes Dev. 2004. PMID: 15198980 Free PMC article.

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