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Response to dietary fat and cholesterol and genetic polymorphisms.
Clifton P, Kind K, Jones C, Noakes M. Clifton P, et al. Clin Exp Pharmacol Physiol. 1997 May;24(5):A21-5. doi: 10.1111/j.1440-1681.1997.tb03049.x. Clin Exp Pharmacol Physiol. 1997. PMID: 9143792 Review.
The response to fat and cholesterol in subjects with at least one apoAIV 2 allele was only 30% of that seen in subjects with the common apoIV 1 allele (P < 0.01), accounting for 6-7% of the variance in response. ...
The response to fat and cholesterol in subjects with at least one apoAIV 2 allele was only 30% of that seen in subjects with the common apoI …
Relationship between plasma insulin and erythrocyte fatty acid composition.
Clifton PM, Nestel PJ. Clifton PM, et al. Prostaglandins Leukot Essent Fatty Acids. 1998 Sep;59(3):191-4. doi: 10.1016/s0952-3278(98)90062-x. Prostaglandins Leukot Essent Fatty Acids. 1998. PMID: 9844992
We found a inverse relationship (r = -0.41, P = 0.002) between fasting plasma insulin and the percentage of arachidonic acid in erythrocyte fatty acids. An inverse relationship of similar strength was found with total n-6 fatty acids and a positive relationship was found w …
We found a inverse relationship (r = -0.41, P = 0.002) between fasting plasma insulin and the percentage of arachidonic acid in eryth …
Diets high and low in glycemic index versus high monounsaturated fat diets: effects on glucose and lipid metabolism in NIDDM.
Luscombe ND, Noakes M, Clifton PM. Luscombe ND, et al. Eur J Clin Nutr. 1999 Jun;53(6):473-8. doi: 10.1038/sj.ejcn.1600779. Eur J Clin Nutr. 1999. PMID: 10403584 Clinical Trial.
RESULTS: HDL-cholesterol was higher on the low-GI and high-mono high-GI diets compared to the high-GI diet (P < 0.05 for overall diet effect). ...

RESULTS: HDL-cholesterol was higher on the low-GI and high-mono high-GI diets compared to the high-GI diet (P < 0.05 for overall d

Effect of weight reduction on the distribution of apolipoprotein A-I in high-density lipoprotein subfractions in obese non-insulin-dependent diabetic subjects.
Shige H, Nestel P, Sviridov D, Noakes M, Clifton P. Shige H, et al. Metabolism. 2000 Nov;49(11):1453-9. doi: 10.1053/meta.2000.17668. Metabolism. 2000. PMID: 11092511 Clinical Trial.
Effects of energy-restricted diets containing increased protein on weight loss, resting energy expenditure, and the thermic effect of feeding in type 2 diabetes.
Luscombe ND, Clifton PM, Noakes M, Parker B, Wittert G. Luscombe ND, et al. Diabetes Care. 2002 Apr;25(4):652-7. doi: 10.2337/diacare.25.4.652. Diabetes Care. 2002. PMID: 11919120 Clinical Trial.

RESULTS: The mean weight loss was 4.6 +/- 0.4 kg (P < 0.001), of which 4.5 +/- 0.4 kg was fat (P < 0.001), with no effect of diet (P = 0.6). ...REE and TEF were reduced similarly with each of the diets (time effects, P = 0.02 and P < 0.

RESULTS: The mean weight loss was 4.6 +/- 0.4 kg (P < 0.001), of which 4.5 +/- 0.4 kg was fat (P < 0.001), with no effec

Dietary composition in restoring reproductive and metabolic physiology in overweight women with polycystic ovary syndrome.
Moran LJ, Noakes M, Clifton PM, Tomlinson L, Galletly C, Norman RJ. Moran LJ, et al. J Clin Endocrinol Metab. 2003 Feb;88(2):812-9. doi: 10.1210/jc.2002-020815. J Clin Endocrinol Metab. 2003. PMID: 12574218 Clinical Trial.
Improvements in menstrual cyclicity were associated with greater decreases in insulin resistance and fasting insulin (P = 0.011). On the LP diet, high density lipoprotein cholesterol decreased 10% during energy restriction (P = 0.008), and the free androgen index in …
Improvements in menstrual cyclicity were associated with greater decreases in insulin resistance and fasting insulin (P = 0.011). On …
Trans fatty acids in adipose tissue and the food supply are associated with myocardial infarction.
Clifton PM, Keogh JB, Noakes M. Clifton PM, et al. J Nutr. 2004 Apr;134(4):874-9. doi: 10.1093/jn/134.4.874. J Nutr. 2004. PMID: 15051840

Cases biopsied before mid-1996 had greater levels of trans 18:1(n-9) (32% P < 0.03) and trans 18:1(n-11) (23%, P < 0.001) than controls biopsied before mid-1996. ...Logistic regression showed that trans 18:1(n-11) (P = 0.03) was an independent predictor

Cases biopsied before mid-1996 had greater levels of trans 18:1(n-9) (32% P < 0.03) and trans 18:1(n-11) (23%, P < 0.001

Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition.
Moran LJ, Noakes M, Clifton PM, Wittert GA, Tomlinson L, Galletly C, Luscombe ND, Norman RJ. Moran LJ, et al. J Clin Endocrinol Metab. 2004 Jul;89(7):3337-44. doi: 10.1210/jc.2003-031583. J Clin Endocrinol Metab. 2004. PMID: 15240612 Clinical Trial.
Non-PCOS subjects had a 70% higher fasting baseline ghrelin (P = 0.011), greater increase in fasting ghrelin (57.5 vs. 34.0%, P = 0.033), and greater maximal decrease in postprandial ghrelin after weight loss (-144.1 +/- 58.4 vs. -28.9 +/- 14.2 pg/ml, P = 0.0 …
Non-PCOS subjects had a 70% higher fasting baseline ghrelin (P = 0.011), greater increase in fasting ghrelin (57.5 vs. 34.0%, P
The satiating effect of dietary protein is unrelated to postprandial ghrelin secretion.
Moran LJ, Luscombe-Marsh ND, Noakes M, Wittert GA, Keogh JB, Clifton PM. Moran LJ, et al. J Clin Endocrinol Metab. 2005 Sep;90(9):5205-11. doi: 10.1210/jc.2005-0701. Epub 2005 Jul 12. J Clin Endocrinol Metab. 2005. PMID: 16014402 Clinical Trial.
Postprandial hunger decreased with weight loss (P = 0.018) and was predicted by changes in fasting and postprandial ghrelin (r2 = 0.246; P = 0.004). Lean mass was the best predictor of fasting (r2 = 0.182; P = 0.003) and postprandial ghrelin (r2 = 0.096; P
Postprandial hunger decreased with weight loss (P = 0.018) and was predicted by changes in fasting and postprandial ghrelin (r2 = 0.2 …
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