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Clinical Outcomes of Moderately Hypofractionated Concurrent Chemoradiotherapy for Newly Diagnosed Glioblastoma.
Kim N, Lim DH, Choi JW, Lee JI, Kong DS, Seol HJ, Nam DH. Kim N, et al. Yonsei Med J. 2023 Feb;64(2):94-103. doi: 10.3349/ymj.2022.0352. Yonsei Med J. 2023. PMID: 36719016 Free PMC article.
PURPOSE: Hypofractionated radiotherapy (HypoRT) has recently been implemented in patients with glioblastoma (GBM) receiving concurrent temozolomide. Lymphopenia during treatment (LDT) is considered an important prognostic factor of clinical outcomes
PURPOSE: Hypofractionated radiotherapy (HypoRT) has recently been implemented in patients with glioblastoma (GBM) receiving …
Treatment of newly diagnosed glioblastoma in the elderly: a network meta-analysis.
Hanna C, Lawrie TA, Rogozińska E, Kernohan A, Jefferies S, Bulbeck H, Ali UM, Robinson T, Grant R. Hanna C, et al. Cochrane Database Syst Rev. 2020 Mar 23;3(3):CD013261. doi: 10.1002/14651858.CD013261.pub2. Cochrane Database Syst Rev. 2020. PMID: 32202316 Free PMC article.
BACKGROUND: A glioblastoma is a fatal type of brain tumour for which the standard of care is maximum surgical resection followed by chemoradiotherapy, when possible. ...Adding BEV to CRT probably increases the risk of thromboembolism (RR 16.63, 95% CI 1.00 to …
BACKGROUND: A glioblastoma is a fatal type of brain tumour for which the standard of care is maximum surgical resection follow …
Optimal adjuvant therapy in elderly glioblastoma: results from a systematic review and network meta-analysis.
Kalra B, Kannan S, Gupta T. Kalra B, et al. J Neurooncol. 2020 Jan;146(2):311-320. doi: 10.1007/s11060-019-03375-w. Epub 2020 Jan 1. J Neurooncol. 2020. PMID: 31894517
Using SUCRA, the surface area for moderately hypofractionated RT (3-weeks) with concurrent and adjuvant temozolomide reached almost 100%, confirming it as the best intervention. As expected, best supportive care alone was ranked as the worst treatment …
Using SUCRA, the surface area for moderately hypofractionated RT (3-weeks) with concurrent and adjuvant temozolomide re …