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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1929 1
1941 1
1945 1
1947 3
1948 3
1949 1
1950 2
1951 2
1954 2
1956 1
1957 1
1958 1
1961 1
1962 4
1963 5
1964 4
1965 1
1966 1
1967 2
1968 5
1969 3
1970 4
1971 1
1972 3
1973 6
1974 4
1975 9
1976 3
1977 4
1978 2
1979 10
1980 8
1981 8
1982 7
1983 7
1984 6
1985 4
1986 10
1987 7
1988 4
1989 3
1990 9
1991 4
1992 6
1993 6
1994 5
1995 6
1996 10
1997 13
1998 11
1999 8
2000 7
2001 5
2002 3
2003 4
2004 3
2005 8
2006 11
2007 12
2008 15
2009 11
2010 9
2011 16
2012 19
2013 12
2014 13
2015 22
2016 19
2017 14
2018 18
2019 15
2020 26
2021 16
2022 19
2023 24
2024 25

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536 results

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Page 1
Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer.
Jia D, Wang Q, Qi Y, Jiang Y, He J, Lin Y, Sun Y, Xu J, Chen W, Fan L, Yan R, Zhang W, Ren G, Xu C, Ge Q, Wang L, Liu W, Xu F, Wu P, Wang Y, Chen S, Wang L. Jia D, et al. Cell. 2024 Mar 28;187(7):1651-1665.e21. doi: 10.1016/j.cell.2024.02.022. Epub 2024 Mar 14. Cell. 2024. PMID: 38490195
Mechanistically, Lactobacillus johnsonii collaborates with Clostridium sporogenes to produce IPA. IPA modulates the stemness program of CD8(+) T cells and facilitates the generation of progenitor exhausted CD8(+) T cells (T(pex)) by increasing H3K27 acetylation at t …
Mechanistically, Lactobacillus johnsonii collaborates with Clostridium sporogenes to produce IPA. IPA modulates the stemness p …
Gut Clostridium sporogenes-derived indole propionic acid suppresses osteoclast formation by activating pregnane X receptor.
Peng R, Song C, Gou S, Liu H, Kang H, Dong Y, Xu Y, Hu P, Cai K, Feng Q, Guan H, Li F. Peng R, et al. Pharmacol Res. 2024 Apr;202:107121. doi: 10.1016/j.phrs.2024.107121. Epub 2024 Feb 29. Pharmacol Res. 2024. PMID: 38431091 Free article.
However, the role of the gut microbiome in estrogen deficiency-induced bone loss and its underlying mechanism remain unknown. In this study, we found that the abundance of Clostridium sporogenes (C. spor.) and its derived metabolite, indole propionic acid (IPA), wer …
However, the role of the gut microbiome in estrogen deficiency-induced bone loss and its underlying mechanism remain unknown. In this study, …
Susceptibility of Clostridium sporogenes Spores to Selected Reference Substances and Disinfectants.
Chojecka A. Chojecka A. Pol J Microbiol. 2022 Sep 24;71(3):353-358. doi: 10.33073/pjm-2022-031. eCollection 2022 Sep 1. Pol J Microbiol. 2022. PMID: 36185021 Free PMC article.
Research on the susceptibility of the spores of anaerobic bacteria such as Clostridium sporogenes or Clostridioides difficile is vital for assessing the sporicidal activity of disinfectants. ...
Research on the susceptibility of the spores of anaerobic bacteria such as Clostridium sporogenes or Clostridioides difficile …
The gut metabolite indole-3 propionate promotes nerve regeneration and repair.
Serger E, Luengo-Gutierrez L, Chadwick JS, Kong G, Zhou L, Crawford G, Danzi MC, Myridakis A, Brandis A, Bello AT, Müller F, Sanchez-Vassopoulos A, De Virgiliis F, Liddell P, Dumas ME, Strid J, Mani S, Dodd D, Di Giovanni S. Serger E, et al. Nature. 2022 Jul;607(7919):585-592. doi: 10.1038/s41586-022-04884-x. Epub 2022 Jun 22. Nature. 2022. PMID: 35732737
Here we show that IF promotes axonal regeneration after sciatic nerve crush in mice through an unexpected mechanism that relies on the gram-positive gut microbiome and an increase in the gut bacteria-derived metabolite indole-3-propionic acid (IPA) in the serum. IPA production by …
Here we show that IF promotes axonal regeneration after sciatic nerve crush in mice through an unexpected mechanism that relies on the gram- …
Clostridium sporogenes increases fat accumulation in mice by enhancing energy absorption and adipogenesis.
Du L, Wang J, Qiu X, Wang Q, Peng H, Huang J, Yang F, Liu Z, Qi R. Du L, et al. Microbiol Spectr. 2024 Jun 25:e0411623. doi: 10.1128/spectrum.04116-23. Online ahead of print. Microbiol Spectr. 2024. PMID: 38916334 Free article.
Gut bacteria belonging to the Clostridium family play a pivotal role in regulating host energy balance and metabolic homeostasis. As a commensal bacterium, Clostridium sporogenes has been implicated in modulating host energy homeostasis, albeit the underlying mechan …
Gut bacteria belonging to the Clostridium family play a pivotal role in regulating host energy balance and metabolic homeostasis. As a comme …
Clostridium sporogenes bacteremia in an immunocompetent patient.
Abusnina W, Shehata M, Karem E, Koc Z, Khalil E. Abusnina W, et al. IDCases. 2019 Jan 2;15:e00481. doi: 10.1016/j.idcr.2018.e00481. eCollection 2019. IDCases. 2019. PMID: 30656136 Free PMC article.
Isolates that are identified by clinical microbiology laboratories include Clostridium perfrigens species in 20-40% of cases. However, when Clostridium sporogenes is identified, is rarely considered to be pathogenic. We present a case of Clostridium sporog
Isolates that are identified by clinical microbiology laboratories include Clostridium perfrigens species in 20-40% of cases. However, when …
Bacteremia caused by Clostridium sporogenes in an oncological patient.
Cobo FJ, Pérez-Carrasco V, García-Salcedo JA, Navarro-Marí JM. Cobo FJ, et al. Rev Esp Quimioter. 2023 Apr;36(2):217-219. doi: 10.37201/req/111.2022. Epub 2023 Jan 26. Rev Esp Quimioter. 2023. PMID: 36698324 Free PMC article. No abstract available.
Clostridium sporogenes uses reductive Stickland metabolism in the gut to generate ATP and produce circulating metabolites.
Liu Y, Chen H, Van Treuren W, Hou BH, Higginbottom SK, Dodd D. Liu Y, et al. Nat Microbiol. 2022 May;7(5):695-706. doi: 10.1038/s41564-022-01109-9. Epub 2022 May 2. Nat Microbiol. 2022. PMID: 35505245 Free PMC article.
Gut bacteria face a key problem in how they capture enough energy to sustain their growth and physiology. The gut bacterium Clostridium sporogenes obtains its energy by utilizing amino acids in pairs, coupling the oxidation of one to the reduction of another-the Sti …
Gut bacteria face a key problem in how they capture enough energy to sustain their growth and physiology. The gut bacterium Clostridium
Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome.
Mars RAT, Yang Y, Ward T, Houtti M, Priya S, Lekatz HR, Tang X, Sun Z, Kalari KR, Korem T, Bhattarai Y, Zheng T, Bar N, Frost G, Johnson AJ, van Treuren W, Han S, Ordog T, Grover M, Sonnenburg J, D'Amato M, Camilleri M, Elinav E, Segal E, Blekhman R, Farrugia G, Swann JR, Knights D, Kashyap PC. Mars RAT, et al. Cell. 2020 Sep 17;182(6):1460-1473.e17. doi: 10.1016/j.cell.2020.08.007. Epub 2020 Sep 10. Cell. 2020. PMID: 32916129 Free PMC article.
536 results