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The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity.
Gorman JA, Hundhausen C, Errett JS, Stone AE, Allenspach EJ, Ge Y, Arkatkar T, Clough C, Dai X, Khim S, Pestal K, Liggitt D, Cerosaletti K, Stetson DB, James RG, Oukka M, Concannon P, Gale M Jr, Buckner JH, Rawlings DJ. Gorman JA, et al. Among authors: clough c. Nat Immunol. 2017 Jul;18(7):744-752. doi: 10.1038/ni.3766. Epub 2017 May 29. Nat Immunol. 2017. PMID: 28553952 Free PMC article.
The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets.
Gorman JA, Hundhausen C, Kinsman M, Arkatkar T, Allenspach EJ, Clough C, West SE, Thomas K, Eken A, Khim S, Hale M, Oukka M, Jackson SW, Cerosaletti K, Buckner JH, Rawlings DJ. Gorman JA, et al. Among authors: clough c. Front Immunol. 2019 Jan 25;10:44. doi: 10.3389/fimmu.2019.00044. eCollection 2019. Front Immunol. 2019. PMID: 30740104 Free PMC article.
ATG4A regulates human erythroid maturation and mitochondrial clearance.
Stolla MC, Reilly A, Bergantinos R, Stewart S, Thom N, Clough CA, Wellington RC, Stolitenko R, Abkowitz JL, Doulatov S. Stolla MC, et al. Among authors: clough ca. Blood Adv. 2022 Jun 28;6(12):3579-3589. doi: 10.1182/bloodadvances.2021005910. Blood Adv. 2022. PMID: 35443024 Free PMC article.
103 results