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Mycobacterium tuberculosis chaperonin 60.1 inhibits leukocyte diapedesis in a murine model of allergic lung inflammation.
Riffo-Vasquez Y, Coates AR, Page CP, Spina D. Riffo-Vasquez Y, et al. Among authors: coates ar. Am J Respir Cell Mol Biol. 2012 Aug;47(2):245-52. doi: 10.1165/rcmb.2011-0412OC. Epub 2012 Mar 23. Am J Respir Cell Mol Biol. 2012. PMID: 22447969
Mycobacterium tuberculosis chaperonin 10 heptamers self-associate through their biologically active loops.
Roberts MM, Coker AR, Fossati G, Mascagni P, Coates AR, Wood SP. Roberts MM, et al. Among authors: coates ar. J Bacteriol. 2003 Jul;185(14):4172-85. doi: 10.1128/jb.185.14.4172-4185.2003. J Bacteriol. 2003. PMID: 12837792 Free PMC article.
Effect of Mycobacterium tuberculosis chaperonins on bronchial eosinophilia and hyper-responsiveness in a murine model of allergic inflammation.
Riffo-Vasquez Y, Spina D, Page C, Tormay P, Singh M, Henderson B, Coates A. Riffo-Vasquez Y, et al. Clin Exp Allergy. 2004 May;34(5):712-9. doi: 10.1111/j.1365-2222.2004.1931.x. Clin Exp Allergy. 2004. PMID: 15144461
The intercellular signaling activity of the Mycobacterium tuberculosis chaperonin 60.1 protein resides in the equatorial domain.
Tormay P, Coates AR, Henderson B. Tormay P, et al. Among authors: coates ar. J Biol Chem. 2005 Apr 8;280(14):14272-7. doi: 10.1074/jbc.M414158200. Epub 2005 Jan 26. J Biol Chem. 2005. PMID: 15677470
Comparative cell signalling activity of ultrapure recombinant chaperonin 60 proteins from prokaryotes and eukaryotes.
Maguire M, Poole S, Coates AR, Tormay P, Wheeler-Jones C, Henderson B. Maguire M, et al. Among authors: coates ar. Immunology. 2005 Jun;115(2):231-8. doi: 10.1111/j.1365-2567.2005.02155.x. Immunology. 2005. PMID: 15885129 Free PMC article.
Highly homologous Mycobacterium tuberculosis chaperonin 60 proteins with differential CD14 dependencies stimulate cytokine production by human monocytes through cooperative activation of p38 and ERK1/2 mitogen-activated protein kinases.
Lewthwaite JC, Clarkin CE, Coates AR, Poole S, Lawrence RA, Wheeler-Jones CP, Pitsillides AA, Singh M, Henderson B. Lewthwaite JC, et al. Among authors: coates ar. Int Immunopharmacol. 2007 Feb;7(2):230-40. doi: 10.1016/j.intimp.2006.10.005. Epub 2006 Nov 20. Int Immunopharmacol. 2007. PMID: 17178391
A Mycobacterium tuberculosis mutant lacking the groEL homologue cpn60.1 is viable but fails to induce an inflammatory response in animal models of infection.
Hu Y, Henderson B, Lund PA, Tormay P, Ahmed MT, Gurcha SS, Besra GS, Coates AR. Hu Y, et al. Among authors: coates ar. Infect Immun. 2008 Apr;76(4):1535-46. doi: 10.1128/IAI.01078-07. Epub 2008 Jan 28. Infect Immun. 2008. PMID: 18227175 Free PMC article.
Chaperonin 60 and macrophage activation.
Coates AR, Cehovin A, Hu Y. Coates AR, et al. Novartis Found Symp. 2008;291:160-9; discussion 169-72, 221-4. doi: 10.1002/9780470754030.ch12. Novartis Found Symp. 2008. PMID: 18575272
The two homologous chaperonin 60 proteins of Mycobacterium tuberculosis have distinct effects on monocyte differentiation into osteoclasts.
Winrow VR, Mesher J, Meghji S, Morris CJ, Maguire M, Fox S, Coates AR, Tormay P, Blake DR, Henderson B. Winrow VR, et al. Among authors: coates ar. Cell Microbiol. 2008 Oct;10(10):2091-104. doi: 10.1111/j.1462-5822.2008.01193.x. Epub 2008 Jul 10. Cell Microbiol. 2008. PMID: 18616692
Acute and persistent Mycobacterium tuberculosis infections depend on the thiol peroxidase TpX.
Hu Y, Coates AR. Hu Y, et al. Among authors: coates ar. PLoS One. 2009;4(4):e5150. doi: 10.1371/journal.pone.0005150. Epub 2009 Apr 2. PLoS One. 2009. PMID: 19340292 Free PMC article.
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