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Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease.
Cheng DT, Kim DK, Cockayne DA, Belousov A, Bitter H, Cho MH, Duvoix A, Edwards LD, Lomas DA, Miller BE, Reynaert N, Tal-Singer R, Wouters EF, Agustí A, Fabbri LM, Rames A, Visvanathan S, Rennard SI, Jones P, Parmar H, MacNee W, Wolff G, Silverman EK, Mayer RJ, Pillai SG; TESRA and ECLIPSE Investigators. Cheng DT, et al. Among authors: cockayne da. Am J Respir Crit Care Med. 2013 Oct 15;188(8):948-57. doi: 10.1164/rccm.201302-0247OC. Am J Respir Crit Care Med. 2013. PMID: 23947473
Novel Series of Dihydropyridinone P2X7 Receptor Antagonists.
Lopez-Tapia F, Walker KA, Brotherton-Pleiss C, Caroon J, Nitzan D, Lowrie L, Gleason S, Zhao SH, Berger J, Cockayne D, Phippard D, Suttmann R, Fitch WL, Bourdet D, Rege P, Huang X, Broadbent S, Dvorak C, Zhu J, Wagner P, Padilla F, Loe B, Jahangir A, Alker A. Lopez-Tapia F, et al. J Med Chem. 2015 Nov 12;58(21):8413-26. doi: 10.1021/acs.jmedchem.5b00365. Epub 2015 Nov 2. J Med Chem. 2015. PMID: 26460788
Overexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function.
Schnegelsberg B, Sun TT, Cain G, Bhattacharya A, Nunn PA, Ford AP, Vizzard MA, Cockayne DA. Schnegelsberg B, et al. Among authors: cockayne da. Am J Physiol Regul Integr Comp Physiol. 2010 Mar;298(3):R534-47. doi: 10.1152/ajpregu.00367.2009. Epub 2009 Dec 23. Am J Physiol Regul Integr Comp Physiol. 2010. PMID: 20032263 Free PMC article.
Purinoceptors as therapeutic targets for lower urinary tract dysfunction.
Ford AP, Gever JR, Nunn PA, Zhong Y, Cefalu JS, Dillon MP, Cockayne DA. Ford AP, et al. Among authors: cockayne da. Br J Pharmacol. 2006 Feb;147 Suppl 2(Suppl 2):S132-43. doi: 10.1038/sj.bjp.0706637. Br J Pharmacol. 2006. PMID: 16465177 Free PMC article. Review.
40 results