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Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging.
Mazur C, Powers B, Zasadny K, Sullivan JM, Dimant H, Kamme F, Hesterman J, Matson J, Oestergaard M, Seaman M, Holt RW, Qutaish M, Polyak I, Coelho R, Gottumukkala V, Gaut CM, Berridge M, Albargothy NJ, Kelly L, Carare RO, Hoppin J, Kordasiewicz H, Swayze EE, Verma A. Mazur C, et al. Among authors: coelho r. JCI Insight. 2019 Oct 17;4(20):e129240. doi: 10.1172/jci.insight.129240. JCI Insight. 2019. PMID: 31619586 Free PMC article.
The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH).
Skaddan MB, Zhang L, Johnson DS, Zhu A, Zasadny KR, Coelho RV, Kuszpit K, Currier G, Fan KH, Beck EM, Chen L, Drozda SE, Balan G, Niphakis M, Cravatt BF, Ahn K, Bocan T, Villalobos A. Skaddan MB, et al. Among authors: coelho rv. Nucl Med Biol. 2012 Oct;39(7):1058-67. doi: 10.1016/j.nucmedbio.2012.03.011. Epub 2012 May 8. Nucl Med Biol. 2012. PMID: 22571907 Free PMC article.
The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging.
Zhang L, Chen L, Beck EM, Chappie TA, Coelho RV, Doran SD, Fan KH, Helal CJ, Humphrey JM, Hughes Z, Kuszpit K, Lachapelle EA, Lazzaro JT, Lee C, Mather RJ, Patel NC, Skaddan MB, Sciabola S, Verhoest PR, Young JM, Zasadny K, Villalobos A. Zhang L, et al. Among authors: coelho rv. J Med Chem. 2017 Oct 26;60(20):8538-8551. doi: 10.1021/acs.jmedchem.7b01050. Epub 2017 Oct 9. J Med Chem. 2017. PMID: 28957634
Genotoxicity of 2-(3-chlorobenzyloxy)-6-(piperazinyl)pyrazine, a novel 5-hydroxytryptamine2c receptor agonist for the treatment of obesity: role of metabolic activation.
Kalgutkar AS, Dalvie DK, Aubrecht J, Smith EB, Coffing SL, Cheung JR, Vage C, Lame ME, Chiang P, McClure KF, Maurer TS, Coelho RV Jr, Soliman VF, Schildknegt K. Kalgutkar AS, et al. Among authors: coelho rv jr. Drug Metab Dispos. 2007 Jun;35(6):848-58. doi: 10.1124/dmd.106.013649. Epub 2007 Mar 7. Drug Metab Dispos. 2007. PMID: 17344339
Molecular Profile of Variants Potentially Associated with Severe Forms of COVID-19 in Amazonian Indigenous Populations.
Coelho RCC, Martins CLELP, Pastana LF, Rodrigues JCG, Aguiar KEC, Cohen-Paes AN, Gellen LPA, Moraes FCA, Calderaro MCL, de Assunção LA, Monte N, Pereira EEB, Ribeiro-Dos-Santos AM, Ribeiro-do-Santos Â, Rodriguez Burbano RM, de Souza SJ, Guerreiro JF, Assumpção PP, Santos SEBD, Fernandes MR, Santos NPCD. Coelho RCC, et al. Viruses. 2024 Feb 26;16(3):359. doi: 10.3390/v16030359. Viruses. 2024. PMID: 38543725 Free PMC article.
860 results