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A phase I, single and fractionated, ascending-dose study evaluating the safety, pharmacokinetics, pharmacodynamics, and immunogenicity of an erythropoietin mimetic antibody fusion protein (CNTO 528) in healthy male subjects.
Bouman-Thio E, Franson K, Miller B, Getsy J, Cohen A, Bai SA, Yohrling J, Frederick B, Marciniak S, Jiao Q, Jang H, Davis H, Burggraaf J. Bouman-Thio E, et al. J Clin Pharmacol. 2008 Oct;48(10):1197-207. doi: 10.1177/0091270008322907. J Clin Pharmacol. 2008. PMID: 18812609 Clinical Trial.
Clinically important interaction between tedisamil and verapamil.
van Haarst AD, Dijkmans AC, Weimann HJ, Kemme MJ, Bosch JJ, Schoemaker RC, Cohen AF, Burggraaf J. van Haarst AD, et al. Among authors: cohen af. J Clin Pharmacol. 2009 May;49(5):560-7. doi: 10.1177/0091270009332812. Epub 2009 Mar 19. J Clin Pharmacol. 2009. PMID: 19299533 Clinical Trial.
Early stage development of the glycine-1 re-uptake inhibitor SCH 900435: central nervous system effects compared with placebo in healthy men.
Liem-Moolenaar M, Peeters P, Kamerling IM, Hogg C, Holder G, Kleijn HJ, Spaans E, Udo De Haes J, de Kam ML, Franson KL, Cohen AF, van Gerven JM. Liem-Moolenaar M, et al. Among authors: cohen af. Br J Clin Pharmacol. 2013 Jun;75(6):1455-67. doi: 10.1111/bcp.12015. Br J Clin Pharmacol. 2013. PMID: 23116363 Free PMC article. Clinical Trial.
Pharmacodynamic response profiles of anxiolytic and sedative drugs.
Chen X, Broeyer F, de Kam M, Baas J, Cohen A, van Gerven J. Chen X, et al. Br J Clin Pharmacol. 2017 May;83(5):1028-1038. doi: 10.1111/bcp.13204. Epub 2017 Mar 17. Br J Clin Pharmacol. 2017. PMID: 27922194 Free PMC article. Clinical Trial.
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