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Evolution of renal function abnormalities in the db/db mouse that parallels the development of human diabetic nephropathy.
Cohen MP, Clements RS, Hud E, Cohen JA, Ziyadeh FN. Cohen MP, et al. Among authors: cohen ja. Exp Nephrol. 1996 May-Jun;4(3):166-71. Exp Nephrol. 1996. PMID: 8773479
Anti-glycation and anti-albuminuric effects of GLY-230 in human diabetes.
Kennedy L, Solano MP, Meneghini L, Lo M, Cohen MP. Kennedy L, et al. Among authors: cohen mp. Am J Nephrol. 2010;31(2):110-6. doi: 10.1159/000259897. Epub 2009 Nov 17. Am J Nephrol. 2010. PMID: 19923796 Clinical Trial.
Effects of nonenzymatic glycation and fatty acids on functional properties of human albumin.
Lautenslager GT, Shearman CW, Hud E, Cohen MP. Lautenslager GT, et al. Among authors: cohen mp. Metabolism. 2011 Dec;60(12):1683-91. doi: 10.1016/j.metabol.2011.03.022. Epub 2011 May 31. Metabolism. 2011. PMID: 21632076
Amelioration of diabetes-associated abnormalities in the vitreous fluid by an inhibitor of albumin glycation.
Cohen MP, Hud E, Wu VY, Shearman CW. Cohen MP, et al. Invest Ophthalmol Vis Sci. 2008 Nov;49(11):5089-93. doi: 10.1167/iovs.08-1993. Epub 2008 Jul 3. Invest Ophthalmol Vis Sci. 2008. PMID: 18599566
Vitreous fluid of db/db mice exhibits alterations in angiogenic and metabolic factors consistent with early diabetic retinopathy.
Cohen MP, Hud E, Shea E, Shearman CW. Cohen MP, et al. Ophthalmic Res. 2008;40(1):5-9. doi: 10.1159/000111151. Epub 2007 Nov 20. Ophthalmic Res. 2008. PMID: 18025835
Inhibiting albumin glycation attenuates dysregulation of VEGFR-1 and collagen IV subchain production and the development of renal insufficiency.
Cohen MP, Lautenslager GT, Hud E, Shea E, Wang A, Chen S, Shearman CW. Cohen MP, et al. Am J Physiol Renal Physiol. 2007 Feb;292(2):F789-95. doi: 10.1152/ajprenal.00201.2006. Epub 2006 Oct 3. Am J Physiol Renal Physiol. 2007. PMID: 17018845
Evidence linking glycated albumin to altered glomerular nephrin and VEGF expression, proteinuria, and diabetic nephropathy.
Cohen MP, Chen S, Ziyadeh FN, Shea E, Hud EA, Lautenslager GT, Shearman CW. Cohen MP, et al. Kidney Int. 2005 Oct;68(4):1554-61. doi: 10.1111/j.1523-1755.2005.00567.x. Kidney Int. 2005. PMID: 16164632
Increased plasma glycated low-density lipoprotein concentrations in diabetes: a marker of atherogenic risk.
Cohen MP, Jin Y, Lautenslager GT. Cohen MP, et al. Diabetes Technol Ther. 2004 Jun;6(3):348-56. doi: 10.1089/152091504774198043. Diabetes Technol Ther. 2004. PMID: 15198838
Inhibiting albumin glycation in vivo ameliorates glomerular overexpression of TGF-beta1.
Cohen MP, Ziyadeh FN, Hong SW, Shearman CW, Hud E, Lautenslager GT, Iglesias-de la Cruz MC, Chen S. Cohen MP, et al. Kidney Int. 2002 Jun;61(6):2025-32. doi: 10.1046/j.1523-1755.2002.00352.x. Kidney Int. 2002. PMID: 12028443
Normalizing glycated albumin reduces increased urinary collagen IV and prevents renal insufficiency in diabetic db/db mice.
Cohen MP, Hud E, Shea E, Shearman CW. Cohen MP, et al. Metabolism. 2002 Jul;51(7):901-5. doi: 10.1053/meta.2002.33359. Metabolism. 2002. PMID: 12077739
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