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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B.
Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Cross DA, et al. Nature. 1995 Dec 21-28;378(6559):785-9. doi: 10.1038/378785a0. Nature. 1995. PMID: 8524413
Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with γ-tubulin.
Voss M, Campbell K, Saranzewa N, Campbell DG, Hastie CJ, Peggie MW, Martin-Granados C, Prescott AR, Cohen PT. Voss M, et al. Cell Cycle. 2013 Sep 1;12(17):2876-87. doi: 10.4161/cc.25919. Epub 2013 Aug 2. Cell Cycle. 2013. PMID: 23966160 Free PMC article.
R3F, a novel membrane-associated glycogen targeting subunit of protein phosphatase 1 regulates glycogen synthase in astrocytoma cells in response to glucose and extracellular signals.
Kelsall IR, Voss M, Munro S, Cuthbertson DJ, Cohen PT. Kelsall IR, et al. J Neurochem. 2011 Aug;118(4):596-610. doi: 10.1111/j.1471-4159.2011.07345.x. Epub 2011 Jul 1. J Neurochem. 2011. PMID: 21668450
Ppm1E is an in cellulo AMP-activated protein kinase phosphatase.
Voss M, Paterson J, Kelsall IR, Martín-Granados C, Hastie CJ, Peggie MW, Cohen PT. Voss M, et al. Cell Signal. 2011 Jan;23(1):114-24. doi: 10.1016/j.cellsig.2010.08.010. Epub 2010 Aug 27. Cell Signal. 2011. PMID: 20801214
Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases.
Martin-Granados C, Philp A, Oxenham SK, Prescott AR, Cohen PT. Martin-Granados C, et al. Int J Biochem Cell Biol. 2008;40(10):2315-32. doi: 10.1016/j.biocel.2008.03.021. Epub 2008 Apr 8. Int J Biochem Cell Biol. 2008. PMID: 18487071
The hepatic PP1 glycogen-targeting subunit interaction with phosphorylase a can be blocked by C-terminal tyrosine deletion or an indole drug.
Kelsall IR, Munro S, Hallyburton I, Treadway JL, Cohen PT. Kelsall IR, et al. FEBS Lett. 2007 Oct 2;581(24):4749-53. doi: 10.1016/j.febslet.2007.08.073. Epub 2007 Sep 6. FEBS Lett. 2007. PMID: 17870073
The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin.
Hastie CJ, Vázquez-Martin C, Philp A, Stark MJ, Cohen PT. Hastie CJ, et al. FEBS J. 2006 Jul;273(14):3322-34. doi: 10.1111/j.1742-4658.2006.05336.x. FEBS J. 2006. PMID: 16857015
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