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The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment.
Breedveld FC, Weisman MH, Kavanaugh AF, Cohen SB, Pavelka K, van Vollenhoven R, Sharp J, Perez JL, Spencer-Green GT. Breedveld FC, et al. Among authors: cohen sb. Arthritis Rheum. 2006 Jan;54(1):26-37. doi: 10.1002/art.21519. Arthritis Rheum. 2006. PMID: 16385520 Clinical Trial.
Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial.
Cohen S, Hurd E, Cush J, Schiff M, Weinblatt ME, Moreland LW, Kremer J, Bear MB, Rich WJ, McCabe D. Cohen S, et al. Arthritis Rheum. 2002 Mar;46(3):614-24. doi: 10.1002/art.10141. Arthritis Rheum. 2002. PMID: 11920396 Clinical Trial.
Costimulatory blockade in patients with rheumatoid arthritis: a pilot, dose-finding, double-blind, placebo-controlled clinical trial evaluating CTLA-4Ig and LEA29Y eighty-five days after the first infusion.
Moreland LW, Alten R, Van den Bosch F, Appelboom T, Leon M, Emery P, Cohen S, Luggen M, Shergy W, Nuamah I, Becker JC. Moreland LW, et al. Arthritis Rheum. 2002 Jun;46(6):1470-9. doi: 10.1002/art.10294. Arthritis Rheum. 2002. PMID: 12115176 Clinical Trial.
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