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S6-haploinsufficiency activates the p53 tumor suppressor.
Panić L, Montagne J, Cokarić M, Volarević S. Panić L, et al. Among authors: cokaric m. Cell Cycle. 2007 Jan 1;6(1):20-4. doi: 10.4161/cc.6.1.3666. Epub 2007 Jan 29. Cell Cycle. 2007. PMID: 17245121 Review.
The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival.
Barkić M, Crnomarković S, Grabusić K, Bogetić I, Panić L, Tamarut S, Cokarić M, Jerić I, Vidak S, Volarević S. Barkić M, et al. Among authors: cokaric m. Mol Cell Biol. 2009 May;29(10):2489-504. doi: 10.1128/MCB.01588-08. Epub 2009 Mar 9. Mol Cell Biol. 2009. PMID: 19273598 Free PMC article.