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Multidrug resistance associated with overexpression of MRP.
Cole SP, Deeley RG. Cole SP, et al. Cancer Treat Res. 1996;87:39-62. doi: 10.1007/978-1-4613-1267-3_2. Cancer Treat Res. 1996. PMID: 8886448 Review. No abstract available.
A single point mutation in Drosophila dihydrofolate reductase confers methotrexate resistance to a transgenic CHO cell line.
Neumann K, Al-Batayneh KM, Kuiper MJ, Parsons-Sheldrake J, Tyshenko MG, Flintoff WF, Cole SP, Walker VK. Neumann K, et al. Among authors: cole sp. Genome. 2003 Aug;46(4):707-15. doi: 10.1139/g03-046. Genome. 2003. PMID: 12897877
Preparation of psoralen polymer-lipid hybrid nanoparticles and their reversal of multidrug resistance in MCF-7/ADR cells.
Huang Q, Cai T, Li Q, Huang Y, Liu Q, Wang B, Xia X, Wang Q, Whitney JCC, Cole SPC, Cai Y. Huang Q, et al. Among authors: cole spc. Drug Deliv. 2018 Nov;25(1):1056-1066. doi: 10.1080/10717544.2018.1464084. Drug Deliv. 2018. PMID: 29695174 Free PMC article.
High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4).
Cheung L, Flemming CL, Watt F, Masada N, Yu DM, Huynh T, Conseil G, Tivnan A, Polinsky A, Gudkov AV, Munoz MA, Vishvanath A, Cooper DM, Henderson MJ, Cole SP, Fletcher JI, Haber M, Norris MD. Cheung L, et al. Among authors: cole sp. Biochem Pharmacol. 2014 Sep 1;91(1):97-108. doi: 10.1016/j.bcp.2014.05.023. Epub 2014 Jun 25. Biochem Pharmacol. 2014. PMID: 24973542
N-linked glycans do not affect plasma membrane localization of multidrug resistance protein 4 (MRP4) but selectively alter its prostaglandin E2 transport activity.
Miah MF, Conseil G, Cole SP. Miah MF, et al. Among authors: cole sp. Biochem Biophys Res Commun. 2016 Jan 22;469(4):954-9. doi: 10.1016/j.bbrc.2015.12.095. Epub 2015 Dec 23. Biochem Biophys Res Commun. 2016. PMID: 26721430
Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport.
Jin D, Ni TT, Sun J, Wan H, Amack JD, Yu G, Fleming J, Chiang C, Li W, Papierniak A, Cheepala S, Conseil G, Cole SP, Zhou B, Drummond IA, Schuetz JD, Malicki J, Zhong TP. Jin D, et al. Among authors: cole sp. Nat Cell Biol. 2014 Sep;16(9):841-51. doi: 10.1038/ncb3029. Epub 2014 Aug 31. Nat Cell Biol. 2014. PMID: 25173977 Free PMC article.
Mammalian multidrug-resistance proteins (MRPs).
Slot AJ, Molinski SV, Cole SP. Slot AJ, et al. Among authors: cole sp. Essays Biochem. 2011 Sep 7;50(1):179-207. doi: 10.1042/bse0500179. Essays Biochem. 2011. PMID: 21967058 Review.
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