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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2006 1
2007 2
2008 1
2009 1
2010 2
2012 1
2013 2
2014 1
2015 4
2016 3
2017 4
2018 5
2019 3
2021 2
2022 3
2023 1

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35 results

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Page 1
A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system.
Alterman JF, Godinho BMDC, Hassler MR, Ferguson CM, Echeverria D, Sapp E, Haraszti RA, Coles AH, Conroy F, Miller R, Roux L, Yan P, Knox EG, Turanov AA, King RM, Gernoux G, Mueller C, Gray-Edwards HL, Moser RP, Bishop NC, Jaber SM, Gounis MJ, Sena-Esteves M, Pai AA, DiFiglia M, Aronin N, Khvorova A. Alterman JF, et al. Among authors: coles ah. Nat Biotechnol. 2019 Aug;37(8):884-894. doi: 10.1038/s41587-019-0205-0. Epub 2019 Aug 2. Nat Biotechnol. 2019. PMID: 31375812 Free PMC article.
siRNA goes after diseases of the bone.
Coles AH. Coles AH. Mol Ther Nucleic Acids. 2023 Oct 20;34:102051. doi: 10.1016/j.omtn.2023.102051. eCollection 2023 Dec 12. Mol Ther Nucleic Acids. 2023. PMID: 37916226 Free PMC article. No abstract available.
Bis-choline tetrathiomolybdate prevents copper-induced blood-brain barrier damage.
Borchard S, Raschke S, Zak KM, Eberhagen C, Einer C, Weber E, Müller SM, Michalke B, Lichtmannegger J, Wieser A, Rieder T, Popowicz GM, Adamski J, Klingenspor M, Coles AH, Viana R, Vendelbo MH, Sandahl TD, Schwerdtle T, Plitz T, Zischka H. Borchard S, et al. Among authors: coles ah. Life Sci Alliance. 2021 Dec 2;5(3):e202101164. doi: 10.26508/lsa.202101164. Print 2022 Mar. Life Sci Alliance. 2021. PMID: 34857647 Free PMC article.
RNAi modulation of placental sFLT1 for the treatment of preeclampsia.
Turanov AA, Lo A, Hassler MR, Makris A, Ashar-Patel A, Alterman JF, Coles AH, Haraszti RA, Roux L, Godinho BMDC, Echeverria D, Pears S, Iliopoulos J, Shanmugalingam R, Ogle R, Zsengeller ZK, Hennessy A, Karumanchi SA, Moore MJ, Khvorova A. Turanov AA, et al. Among authors: coles ah. Nat Biotechnol. 2018 Nov 19:10.1038/nbt.4297. doi: 10.1038/nbt.4297. Online ahead of print. Nat Biotechnol. 2018. PMID: 30451990 Free PMC article.
Efficient Gene Silencing in Brain Tumors with Hydrophobically Modified siRNAs.
Osborn MF, Coles AH, Golebiowski D, Echeverria D, Moazami MP, Watts JK, Sena-Esteves M, Khvorova A. Osborn MF, et al. Among authors: coles ah. Mol Cancer Ther. 2018 Jun;17(6):1251-1258. doi: 10.1158/1535-7163.MCT-17-1144. Epub 2018 Apr 13. Mol Cancer Ther. 2018. PMID: 29654062 Free PMC article.
PK-modifying anchors significantly alter clearance kinetics, tissue distribution, and efficacy of therapeutics siRNAs.
Godinho BMDC, Knox EG, Hildebrand S, Gilbert JW, Echeverria D, Kennedy Z, Haraszti RA, Ferguson CM, Coles AH, Biscans A, Caiazzi J, Alterman JF, Hassler MR, Khvorova A. Godinho BMDC, et al. Among authors: coles ah. Mol Ther Nucleic Acids. 2022 Jun 13;29:116-132. doi: 10.1016/j.omtn.2022.06.005. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 35795486 Free PMC article.
Hdac6 regulates Tip60-p400 function in stem cells.
Chen PB, Hung JH, Hickman TL, Coles AH, Carey JF, Weng Z, Chu F, Fazzio TG. Chen PB, et al. Among authors: coles ah. Elife. 2013 Dec 3;2:e01557. doi: 10.7554/eLife.01557. Elife. 2013. PMID: 24302573 Free PMC article.
35 results