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The dual control of TFIIB recruitment by NC2 is gene specific.
Masson P, Leimgruber E, Creton S, Collart MA. Masson P, et al. Nucleic Acids Res. 2008 Feb;36(2):539-49. doi: 10.1093/nar/gkm1078. Epub 2007 Nov 29. Nucleic Acids Res. 2008. PMID: 18048413 Free PMC article.
The Not3/5 subunit of the Ccr4-Not complex: a central regulator of gene expression that integrates signals between the cytoplasm and the nucleus in eukaryotic cells.
Collart MA, Panasenko OO, Nikolaev SI. Collart MA, et al. Cell Signal. 2013 Apr;25(4):743-51. doi: 10.1016/j.cellsig.2012.12.018. Epub 2012 Dec 29. Cell Signal. 2013. PMID: 23280189 Review.
The NC2 alpha and beta subunits play different roles in vivo.
Creton S, Svejstrup JQ, Collart MA. Creton S, et al. Genes Dev. 2002 Dec 15;16(24):3265-76. doi: 10.1101/gad.234002. Genes Dev. 2002. PMID: 12502746 Free PMC article.
The Ccr4-Not Complex: Architecture and Structural Insights.
Collart MA, Panasenko OO. Collart MA, et al. Subcell Biochem. 2017;83:349-379. doi: 10.1007/978-3-319-46503-6_13. Subcell Biochem. 2017. PMID: 28271483 Review.
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