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Analysis of vertebrate vision in a 384-well imaging system.
Thorn RJ, Dombroski A, Eller K, Dominguez-Gonzalez TM, Clift DE, Baek P, Seto RJ, Kahn ES, Tucker SK, Colwill RM, Sello JK, Creton R. Thorn RJ, et al. Sci Rep. 2019 Sep 27;9(1):13989. doi: 10.1038/s41598-019-50372-0. Sci Rep. 2019. PMID: 31562366 Free PMC article.
The current study introduces a novel imaging system for measuring visually-guided behaviors in larval zebrafish. The imaging system is the first to image four 96-well plates with a single camera for automated measurements of activity in a 384-well format. ...
The current study introduces a novel imaging system for measuring visually-guided behaviors in larval zebrafish. The imaging system i …
Behavioral studies of stimulus learning in zebrafish larvae.
Colwill RM. Colwill RM. Behav Processes. 2019 Jul;164:150-156. doi: 10.1016/j.beproc.2019.04.005. Epub 2019 May 2. Behav Processes. 2019. PMID: 31054948 Free PMC article. Review.
Within a week of fertilization, a zebrafish larva has developed a robust behavioral repertoire that includes the ability to learn about noncontingent stimuli. ...For each of these three questions, I also identify those issues regarding stimulus learning in the developing …
Within a week of fertilization, a zebrafish larva has developed a robust behavioral repertoire that includes the ability to learn abo …
The loss and recovery of vertebrate vision examined in microplates.
Thorn RJ, Clift DE, Ojo O, Colwill RM, Creton R. Thorn RJ, et al. PLoS One. 2017 Aug 17;12(8):e0183414. doi: 10.1371/journal.pone.0183414. eCollection 2017. PLoS One. 2017. PMID: 28817700 Free PMC article.
In the present study, we developed novel behavioral assays to examine vision in a vertebrate model system. In the assays, zebrafish larvae are imaged in multiwell or multilane plates while various red, green, blue, yellow or cyan objects are presented to the larvae on a co …
In the present study, we developed novel behavioral assays to examine vision in a vertebrate model system. In the assays, zebrafish l …
Effects of embryonic exposure to polychlorinated biphenyls (PCBs) on anxiety-related behaviors in larval zebrafish.
Gonzalez ST, Remick D, Creton R, Colwill RM. Gonzalez ST, et al. Neurotoxicology. 2016 Mar;53:93-101. doi: 10.1016/j.neuro.2015.12.018. Epub 2015 Dec 31. Neurotoxicology. 2016. PMID: 26748073 Free PMC article.
The zebrafish (Danio rerio) is an excellent model system for assessing the effects of toxicant exposure on behavior and neurodevelopment. ...
The zebrafish (Danio rerio) is an excellent model system for assessing the effects of toxicant exposure on behavior and neurodevelopm …
Effects of embryonic exposure to polychlorinated biphenyls (PCBs) on larval zebrafish behavior.
Lovato AK, Creton R, Colwill RM. Lovato AK, et al. Neurotoxicol Teratol. 2016 Jan-Feb;53:1-10. doi: 10.1016/j.ntt.2015.11.002. Epub 2015 Nov 10. Neurotoxicol Teratol. 2016. PMID: 26561944 Free PMC article.
Developmental disorders such as anxiety, autism, and attention deficit hyperactivity disorders have been linked to exposure to polychlorinated biphenyls (PCBs), a ubiquitous anthropogenic pollutant. The zebrafish is widely recognized as an excellent model system for assess …
Developmental disorders such as anxiety, autism, and attention deficit hyperactivity disorders have been linked to exposure to polychlorinat …
Effects of embryonic cyclosporine exposures on brain development and behavior.
Clift DE, Thorn RJ, Passarelli EA, Kapoor M, LoPiccolo MK, Richendrfer HA, Colwill RM, Creton R. Clift DE, et al. Behav Brain Res. 2015 Apr 1;282:117-24. doi: 10.1016/j.bbr.2015.01.006. Epub 2015 Jan 13. Behav Brain Res. 2015. PMID: 25591474 Free PMC article.
The risk for human brain development is difficult to evaluate because of a lack of basic information on the sensitive developmental times and the potentially pleiotropic effects on brain development and behavior. In the present study, we use zebrafish as a model system to …
The risk for human brain development is difficult to evaluate because of a lack of basic information on the sensitive developmental times an …
High-throughput analysis of behavior in zebrafish larvae: effects of feeding.
Clift D, Richendrfer H, Thorn RJ, Colwill RM, Creton R. Clift D, et al. Zebrafish. 2014 Oct;11(5):455-61. doi: 10.1089/zeb.2014.0989. Epub 2014 Aug 25. Zebrafish. 2014. PMID: 25153037 Free PMC article.
Identification of these factors is facilitated by high-throughput analyses of behavior in zebrafish larvae, which can be imaged in multiwell or multilane plates. However, the nutritional needs of zebrafish larvae during the behavioral experiments are not fully under …
Identification of these factors is facilitated by high-throughput analyses of behavior in zebrafish larvae, which can be imaged in mu …
Single stimulus learning in zebrafish larvae.
O'Neale A, Ellis J, Creton R, Colwill RM. O'Neale A, et al. Neurobiol Learn Mem. 2014 Feb;108:145-54. doi: 10.1016/j.nlm.2013.08.016. Epub 2013 Sep 6. Neurobiol Learn Mem. 2014. PMID: 24012906 Free PMC article.
Learning about a moving visual stimulus was examined in zebrafish larvae using an automated imaging system and a t1-t2 design. In three experiments, zebrafish larvae were exposed to one of two inputs at t1 (either a gray bouncing disk or an identical but stationary …
Learning about a moving visual stimulus was examined in zebrafish larvae using an automated imaging system and a t1-t2 design. In thr …
Developmental sub-chronic exposure to chlorpyrifos reduces anxiety-related behavior in zebrafish larvae.
Richendrfer H, Pelkowski SD, Colwill RM, Créton R. Richendrfer H, et al. Neurotoxicol Teratol. 2012 Jul;34(4):458-65. doi: 10.1016/j.ntt.2012.04.010. Epub 2012 May 8. Neurotoxicol Teratol. 2012. PMID: 22579535 Free PMC article.
In the present study, we examined the effects of sub-chronic chlorpyrifos exposure on anxiety-related behavior during development using zebrafish larvae. We found that sub-chronic exposure to 0.01 or 0.1 muM chlorpyrifos during development induces specific behavioral defec …
In the present study, we examined the effects of sub-chronic chlorpyrifos exposure on anxiety-related behavior during development using z
On the edge: pharmacological evidence for anxiety-related behavior in zebrafish larvae.
Richendrfer H, Pelkowski SD, Colwill RM, Creton R. Richendrfer H, et al. Behav Brain Res. 2012 Mar 1;228(1):99-106. doi: 10.1016/j.bbr.2011.11.041. Epub 2011 Dec 6. Behav Brain Res. 2012. PMID: 22155488 Free PMC article.
Zebrafish larvae are ideally suited for high-throughput analyses of vertebrate behavior. ...Although there are substantial differences between zebrafish and human brains, our results indicate that the signals that regulate anxiety are similar on a molecular level. .
Zebrafish larvae are ideally suited for high-throughput analyses of vertebrate behavior. ...Although there are substantial difference
14 results