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Efficacy and safety of hyaluronic acid in treatment of leg ulcers: a double-blind RCT.
Dereure O, Czubek M, Combemale P. Dereure O, et al. Among authors: combemale p. J Wound Care. 2012 Mar;21(3):131-2, 134-6, 138-9. doi: 10.12968/jowc.2012.21.3.131. J Wound Care. 2012. PMID: 22399081 Clinical Trial.
At day 45, the percentage of ulcer surface reduction was significantly greater in the hyaluronic acid treatment group (39 ± 6%) compared with the neutral vehicle (control) group (5 ± 9%) (p=0.002). ...From day 0 to day 45, pain intensity (VA S) decreased by mean 9.8 ± 3.5m …
At day 45, the percentage of ulcer surface reduction was significantly greater in the hyaluronic acid treatment group (39 ± 6%) compared wit …
Malignancy and chronic leg ulcers: the value of systematic wound biopsies: a prospective, multicenter, cross-sectional study.
Senet P, Combemale P, Debure C, Baudot N, Machet L, Aout M, Vicaut E, Lok C; Angio-Dermatology Group Of The French Society Of Dermatology. Senet P, et al. Among authors: combemale p. Arch Dermatol. 2012 Jun;148(6):704-8. doi: 10.1001/archdermatol.2011.3362. Arch Dermatol. 2012. PMID: 22772403 Clinical Trial.
Evaluation of a new moisturizer (Exomega milk) in children with atopic dermatitis.
Giordano-Labadie F, Cambazard F, Guillet G, Combemale P, Mengeaud V. Giordano-Labadie F, et al. Among authors: combemale p. J Dermatolog Treat. 2006;17(2):78-81. doi: 10.1080/09546630600552216. J Dermatolog Treat. 2006. PMID: 16766330 Clinical Trial.
After 2 months, the decrease of the Scorad index in the treated group was not statistically significant (p = 0.051) but detailed evaluation showed a significant improvement of xerosis (p = 0.01) and pruritus (p = 0.01) in the treated group compared with the n …
After 2 months, the decrease of the Scorad index in the treated group was not statistically significant (p = 0.051) but detailed eval …
Efficacy of a silver lipidocolloid dressing on heavily colonised wounds: a republished RCT.
Lazareth I, Meaume S, Sigal-Grinberg ML, Combemale P, Le Guyadec T, Zagnoli A. Lazareth I, et al. Among authors: combemale p. J Wound Care. 2012 Feb;21(2):96-102. doi: 10.12968/jowc.2012.21.2.96. J Wound Care. 2012. PMID: 22584529 Clinical Trial.
Prognostic factors associated with healing of venous leg ulcers: a multicentre, prospective, cohort study.
Chaby G, Senet P, Ganry O, Caudron A, Thuillier D, Debure C, Meaume S, Truchetet F, Combemale P, Skowron F, Joly P, Lok C; Angio-Dermatology Group of the French Society of Dermatology. Chaby G, et al. Among authors: combemale p. Br J Dermatol. 2013 Nov;169(5):1106-13. doi: 10.1111/bjd.12570. Br J Dermatol. 2013. PMID: 23909381 Clinical Trial.
Univariate analysis significantly associated complete healing with superficial venous surgery (P = 0.001), adherence to compression therapy at W4 (P = 0.03) and W24 (P = 0.01), ankle-joint ankylosis (P = 0.01) and mean percentage of VLU area reduction …
Univariate analysis significantly associated complete healing with superficial venous surgery (P = 0.001), adherence to compression t …
Long-term efficacy and safety of sonidegib in patients with locally advanced and metastatic basal cell carcinoma: 30-month analysis of the randomized phase 2 BOLT study.
Lear JT, Migden MR, Lewis KD, Chang ALS, Guminski A, Gutzmer R, Dirix L, Combemale P, Stratigos A, Plummer R, Castro H, Yi T, Mone M, Zhou J, Trefzer U, Kaatz M, Loquai C, Kudchadkar R, Sellami D, Dummer R. Lear JT, et al. Among authors: combemale p. J Eur Acad Dermatol Venereol. 2018 Mar;32(3):372-381. doi: 10.1111/jdv.14542. Epub 2017 Nov 6. J Eur Acad Dermatol Venereol. 2018. PMID: 28846163 Free PMC article. Clinical Trial.
Evaluation of a lipidocolloid wound dressing in the local management of leg ulcers.
Meaume S, Ourabah Z, Cartier H, Granel-Brocard F, Combemale P, Bressieux JM, Bohbot S. Meaume S, et al. Among authors: combemale p. J Wound Care. 2005 Jul;14(7):329-34. J Wound Care. 2005. PMID: 16048220 Clinical Trial.

Thirty-three local adverse events were recorded in 27 patients: 10 in the Urgotul group and 23 in the DuoDERM E group (p = 0.039). Nurses reported better acceptability for the Urgotul dressing, based on pain on removal, maceration and odour (p < 0.0001). CONCLUSI

Thirty-three local adverse events were recorded in 27 patients: 10 in the Urgotul group and 23 in the DuoDERM E group (p = 0.039). Nu …
Malignant transformation of leg ulcers: a retrospective study of 85 cases.
Combemale P, Bousquet M, Kanitakis J, Bernard P; Angiodermatology Group, French Society of Dermatology. Combemale P, et al. J Eur Acad Dermatol Venereol. 2007 Aug;21(7):935-41. doi: 10.1111/j.1468-3083.2006.02118.x. J Eur Acad Dermatol Venereol. 2007. PMID: 17659003
Maggot therapy for wound debridement: a randomized multicenter trial.
Opletalová K, Blaizot X, Mourgeon B, Chêne Y, Creveuil C, Combemale P, Laplaud AL, Sohyer-Lebreuilly I, Dompmartin A. Opletalová K, et al. Among authors: combemale p. Arch Dermatol. 2012 Apr;148(4):432-8. doi: 10.1001/archdermatol.2011.1895. Epub 2011 Dec 19. Arch Dermatol. 2012. PMID: 22184720 Clinical Trial.
RESULTS: There was a significant difference between groups at day 8 (54.5% in the MDT group and 66.5% in the control group) (P = .04). The mean percentage of slough at day 15 was 55.4% in the MDT group and 53.8% in the control group (P = .78). CONCLUSIONS: Although …
RESULTS: There was a significant difference between groups at day 8 (54.5% in the MDT group and 66.5% in the control group) (P = .04) …
The 12-month analysis from Basal Cell Carcinoma Outcomes with LDE225 Treatment (BOLT): A phase II, randomized, double-blind study of sonidegib in patients with advanced basal cell carcinoma.
Dummer R, Guminski A, Gutzmer R, Dirix L, Lewis KD, Combemale P, Herd RM, Kaatz M, Loquai C, Stratigos AJ, Schulze HJ, Plummer R, Gogov S, Pallaud C, Yi T, Mone M, Chang AL, Cornélis F, Kudchadkar R, Trefzer U, Lear JT, Sellami D, Migden MR. Dummer R, et al. Among authors: combemale p. J Am Acad Dermatol. 2016 Jul;75(1):113-125.e5. doi: 10.1016/j.jaad.2016.02.1226. Epub 2016 Apr 7. J Am Acad Dermatol. 2016. PMID: 27067394 Clinical Trial.
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