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CRAC channelopathies.
Feske S. Feske S. Pflugers Arch. 2010 Jul;460(2):417-35. doi: 10.1007/s00424-009-0777-5. Epub 2010 Jan 29. Pflugers Arch. 2010. PMID: 20111871 Free PMC article. Review.
Both proteins are widely expressed in many tissues in both human and mouse consistent with the widespread prevalence of SOCE and CRAC channel currents in many cells types. CRAC channelopathies in human patients with mutations in STIM1 and ORAI1 are characterized by abolish …
Both proteins are widely expressed in many tissues in both human and mouse consistent with the widespread prevalence of SOCE and CRAC channe …
Biochemical and functional properties of the store-operated Ca2+ channels.
Salido GM, Sage SO, Rosado JA. Salido GM, et al. Cell Signal. 2009 Apr;21(4):457-61. doi: 10.1016/j.cellsig.2008.11.005. Epub 2008 Nov 13. Cell Signal. 2009. PMID: 19049864 Review.
The recent identification of the proteins stromal interaction molecule 1 (STIM1) and Orai1 has shed new light on the nature and regulation of SOC channels. STIM1 has been presented as the endoplasmic reticulum (ER) Ca(2+) sensor that communicates the content of the …
The recent identification of the proteins stromal interaction molecule 1 (STIM1) and Orai1 has shed new light on the nature and regul …
The critical role of STIM1-dependent Ca2+ signalling during T-cell development and activation.
Samakai E, Hooper R, Soboloff J. Samakai E, et al. Int J Biochem Cell Biol. 2013 Nov;45(11):2491-5. doi: 10.1016/j.biocel.2013.07.014. Epub 2013 Jul 29. Int J Biochem Cell Biol. 2013. PMID: 23906672 Free PMC article. Review.
Although the role of STIM1 in T cell activation has been extensively investigated, the role of STIM1 in T cell development has been somewhat controversial. Indeed, deficiencies in STIM1 expression and function lead to both developmental defects associa …
Although the role of STIM1 in T cell activation has been extensively investigated, the role of STIM1 in T cell development has …