Combs D - Search Results

1

Pharmacokinetics and pharmacodynamics of tenecteplase in fibrinolytic therapy of acute myocardial infarction.

Tanswell P, Modi N, Combs D, Danays T. Tanswell P, et al. Among authors: combs d. Clin Pharmacokinet. 2002;41(15):1229-45. doi: 10.2165/00003088-200241150-00001. Clin Pharmacokinet. 2002. PMID: 12452736 Review.

2

A target-mediated model to describe the pharmacokinetics and hemodynamic effects of recombinant human vascular endothelial growth factor in humans.

Eppler SM, Combs DL, Henry TD, Lopez JJ, Ellis SG, Yi JH, Annex BH, McCluskey ER, Zioncheck TF. Eppler SM, et al. Among authors: combs dl. Clin Pharmacol Ther. 2002 Jul;72(1):20-32. doi: 10.1067/mcp.2002.126179. Clin Pharmacol Ther. 2002. PMID: 12152001 Clinical Trial.

3

Depletion of B cells by a humanized anti-CD20 antibody PRO70769 in Macaca fascicularis.

Vugmeyster Y, Beyer J, Howell K, Combs D, Fielder P, Yang J, Qureshi F, Sandlund B, Kawaguchi L, Dummer W, Lowman H, McKeever K. Vugmeyster Y, et al. Among authors: combs d. J Immunother. 2005 May-Jun;28(3):212-9. doi: 10.1097/01.cji.0000155050.03916.04. J Immunother. 2005. PMID: 15838377

4

Rituximab therapy for CNS lymphomas: targeting the leptomeningeal compartment.

Rubenstein JL, Combs D, Rosenberg J, Levy A, McDermott M, Damon L, Ignoffo R, Aldape K, Shen A, Lee D, Grillo-Lopez A, Shuman MA. Rubenstein JL, et al. Among authors: combs d. Blood. 2003 Jan 15;101(2):466-8. doi: 10.1182/blood-2002-06-1636. Epub 2002 Sep 5. Blood. 2003. PMID: 12393404

5

Albumin binding as a general strategy for improving the pharmacokinetics of proteins.

Dennis MS, Zhang M, Meng YG, Kadkhodayan M, Kirchhofer D, Combs D, Damico LA. Dennis MS, et al. Among authors: combs d. J Biol Chem. 2002 Sep 20;277(38):35035-43. doi: 10.1074/jbc.M205854200. Epub 2002 Jul 15. J Biol Chem. 2002. PMID: 12119302

6

Population pharmacokinetics of rituximab (anti-CD20 monoclonal antibody) in rheumatoid arthritis patients during a phase II clinical trial.

Ng CM, Bruno R, Combs D, Davies B. Ng CM, et al. Among authors: combs d. J Clin Pharmacol. 2005 Jul;45(7):792-801. doi: 10.1177/0091270005277075. J Clin Pharmacol. 2005. PMID: 15951469 Clinical Trial.

7

Albumin affinity tags increase peptide half-life in vivo.

Koehler MF, Zobel K, Beresini MH, Caris LD, Combs D, Paasch BD, Lazarus RA. Koehler MF, et al. Among authors: combs d. Bioorg Med Chem Lett. 2002 Oct 21;12(20):2883-6. doi: 10.1016/s0960-894x(02)00610-8. Bioorg Med Chem Lett. 2002. PMID: 12270169

8

Phosphate ester serum albumin affinity tags greatly improve peptide half-life in vivo.

Zobel K, Koehler MF, Beresini MH, Caris LD, Combs D. Zobel K, et al. Among authors: combs d. Bioorg Med Chem Lett. 2003 May 5;13(9):1513-5. doi: 10.1016/s0960-894x(03)00209-9. Bioorg Med Chem Lett. 2003. PMID: 12699744

9

Chiral kinetics and dynamics of ketorolac.

Mroszczak E, Combs D, Chaplin M, Tsina I, Tarnowski T, Rocha C, Tam Y, Boyd A, Young J, Depass L. Mroszczak E, et al. Among authors: combs d. J Clin Pharmacol. 1996 Jun;36(6):521-39. doi: 10.1002/j.1552-4604.1996.tb05042.x. J Clin Pharmacol. 1996. PMID: 8809637

10

Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacological Effect of Orally Administered CORT125134: An Adaptive, Double-Blind, Randomized, Placebo-Controlled Phase 1 Clinical Study.

Hunt H, Donaldson K, Strem M, Zann V, Leung P, Sweet S, Connor A, Combs D, Belanoff J. Hunt H, et al. Among authors: combs d. Clin Pharmacol Drug Dev. 2018 May;7(4):408-421. doi: 10.1002/cpdd.389. Epub 2017 Oct 2. Clin Pharmacol Drug Dev. 2018. PMID: 28967708 Free PMC article. Clinical Trial.

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