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Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: relevance to xenobiotic metabolism and toxicity.
Wormhoudt LW, Commandeur JN, Vermeulen NP. Wormhoudt LW, et al. Among authors: commandeur jn. Crit Rev Toxicol. 1999 Jan;29(1):59-124. doi: 10.1080/10408449991349186. Crit Rev Toxicol. 1999. PMID: 10066160 Review.
Mutagenicity and cytotoxicity of two regioisomeric mercapturic acids and cysteine S-conjugates of trichloroethylene.
Commandeur JN, Boogaard PJ, Mulder GJ, Vermeulen NP. Commandeur JN, et al. Arch Toxicol. 1991;65(5):373-80. doi: 10.1007/BF02284259. Arch Toxicol. 1991. PMID: 1929851
Identification of N-acetyl(2,2-dichlorovinyl)- and N-acetyl(1,2-dichlorovinyl)-L-cysteine as two regioisomeric mercapturic acids of trichloroethylene in the rat.
Commandeur JN, Vermeulen NP. Commandeur JN, et al. Chem Res Toxicol. 1990 May-Jun;3(3):212-8. doi: 10.1021/tx00015a005. Chem Res Toxicol. 1990. PMID: 1966701
Metabolism of L-cysteine S-conjugates and N-(trideuteroacetyl)-L-cysteine S-conjugates of four fluoroethylenes in the rat. Role of balance of deacetylation and acetylation in relation to the nephrotoxicity of mercapturic acids.
Commandeur JN, Stijntjes GJ, Wijngaard J, Vermeulen NP. Commandeur JN, et al. Biochem Pharmacol. 1991 Jun 21;42(1):31-8. doi: 10.1016/0006-2952(91)90677-w. Biochem Pharmacol. 1991. PMID: 2069595
Induction of drug metabolism enzymes by dihalogenated biphenyls.
van Bree L, Commandeur J, Lamberts B, Cornelissen M, van Roon M, Laterveer H, de Vries J. van Bree L, et al. J Biochem Toxicol. 1990 Spring;5(1):57-63. doi: 10.1002/jbt.2570050109. J Biochem Toxicol. 1990. PMID: 2119436
Molecular and biochemical mechanisms of chemically induced nephrotoxicity: a review.
Commandeur JN, Vermeulen NP. Commandeur JN, et al. Chem Res Toxicol. 1990 May-Jun;3(3):171-94. doi: 10.1021/tx00015a001. Chem Res Toxicol. 1990. PMID: 2131829 Review. No abstract available.
A predictive substrate model for rat glutathione S-transferase 4-4.
de Groot MJ, van der Aar EM, Nieuwenhuizen PJ, van der Plas RM, Donné-Op den Kelder GM, Commandeur JN, Vermeulen NP. de Groot MJ, et al. Among authors: commandeur jn. Chem Res Toxicol. 1995 Jul-Aug;8(5):649-58. doi: 10.1021/tx00047a004. Chem Res Toxicol. 1995. PMID: 7548747
Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Role in bioactivation and detoxication mechanisms of xenobiotics.
Commandeur JN, Stijntjes GJ, Vermeulen NP. Commandeur JN, et al. Pharmacol Rev. 1995 Jun;47(2):271-330. Pharmacol Rev. 1995. PMID: 7568330 Review. No abstract available.
Metabolite predictions for para-substituted anisoles based on ab initio complete active space self-consistent field calculations.
de Groot MJ, Donné-Op den Kelder GM, Commandeur JN, van Lenthe JH, Vermeulen NP. de Groot MJ, et al. Among authors: commandeur jn. Chem Res Toxicol. 1995 Apr-May;8(3):437-43. doi: 10.1021/tx00045a016. Chem Res Toxicol. 1995. PMID: 7578931
Metabolism and kinetics of trichloroethylene in relation to toxicity and carcinogenicity. Relevance of the mercapturic acid pathway.
Goeptar AR, Commandeur JN, van Ommen B, van Bladeren PJ, Vermeulen NP. Goeptar AR, et al. Among authors: commandeur jn. Chem Res Toxicol. 1995 Jan-Feb;8(1):3-21. doi: 10.1021/tx00043a001. Chem Res Toxicol. 1995. PMID: 7703363 Review. No abstract available.
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