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Comorbidity Profiles of Posttraumatic Stress Disorder Across the Medical Phenome.
Hicks EM, Niarchou M, Goleva S, Kabir D, Ciarcia J; PTSD & Trauma EHR Working Group; Smoller JW, Davis LK, Nievergelt CM, Koenen KC, Huckins LM, Choi KW. Hicks EM, et al. medRxiv [Preprint]. 2023 Aug 28:2023.08.25.23294572. doi: 10.1101/2023.08.25.23294572. medRxiv. 2023. Update in: Biol Psychiatry Glob Open Sci. 2024 May 29;4(5):100337. doi: 10.1016/j.bpsgos.2024.100337 PMID: 37693435 Free PMC article. Updated. Preprint.
METHODS: PTSD was defined among biobank participants (total N=123,365) in a major healthcare system using two ICD code-based definitions: broad (1+ PTSD or acute stress codes versus 0; N(Case)=14,899) and narrow (2+ PTSD codes versus 0; N(Case)=3,026). Using a phenome …
METHODS: PTSD was defined among biobank participants (total N=123,365) in a major healthcare system using two ICD code-based definitions: br …
Comorbidity Profiles of Posttraumatic Stress Disorder Across the Medical Phenome.
Hicks EM, Niarchou M, Goleva S, Kabir D, Johnson J, Johnston KJA, Ciarcia J, Pathak GA, Smoller JW, Davis LK, Nievergelt CM, Koenen KC, Huckins LM, Choi KW; PGC/PsycheMERGE PTSD & Trauma EHR Working Group. Hicks EM, et al. Biol Psychiatry Glob Open Sci. 2024 May 29;4(5):100337. doi: 10.1016/j.bpsgos.2024.100337. eCollection 2024 Sep. Biol Psychiatry Glob Open Sci. 2024. PMID: 39050781 Free PMC article.
BACKGROUND: Previous epidemiological research has linked posttraumatic stress disorder (PTSD) with specific physical health problems, but the comprehensive landscape of medical conditions associated with PTSD remains uncharacterized. ...Posttraumati …
BACKGROUND: Previous epidemiological research has linked posttraumatic stress disorder (PTSD) with specific physical he …
Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits.
Pathak GA, Singh K, Wendt FR, Fleming TW, Overstreet C, Koller D, Tylee DS, De Angelis F, Cabrera Mendoza B, Levey DF, Koenen KC, Krystal JH, Pietrzak RH, O' Donell C, Gaziano JM, Falcone G, Stein MB, Gelernter J, Pasaniuc B, Mancuso N, Davis LK, Polimanti R. Pathak GA, et al. Mol Psychiatry. 2022 Mar;27(3):1394-1404. doi: 10.1038/s41380-022-01488-9. Epub 2022 Mar 3. Mol Psychiatry. 2022. PMID: 35241783 Free PMC article.
Posttraumatic stress disorder (PTSD) is a psychiatric disorder that may arise in response to severe traumatic event and is diagnosed based on three main symptom clusters (reexperiencing, avoidance, and hyperarousal) per the Diagnostic Manual of Mental …
Posttraumatic stress disorder (PTSD) is a psychiatric disorder that may arise in response to severe traumatic ev …
Diagnostic profiles among suicide decedents with and without borderline personality disorder.
Kaufman EA, Coon H, Shabalin AA, Monson ET, Chen D, Staley MJ, Keeshin BR, Docherty AR, Bakian AV, DiBlasi E. Kaufman EA, et al. Psychol Med. 2024 Nov 18:1-10. doi: 10.1017/S0033291724002034. Online ahead of print. Psychol Med. 2024. PMID: 39552384
BACKGROUND: Borderline personality disorder (BPD) is a debilitating condition characterized by pervasive instability across multiple major domains of functioning. ...RESULTS: Multivariable logistic regression models revealed that persons with BPD who died by suicide …
BACKGROUND: Borderline personality disorder (BPD) is a debilitating condition characterized by pervasive instability across mu …
Comorbidity classes and associated impairment, demographics and 9/11-exposures in 8,236 children and adolescents.
Geronazzo-Alman L, Guffanti G, Eisenberg R, Fan B, Musa GJ, Wicks J, Bresnahan M, Duarte CS, Hoven C. Geronazzo-Alman L, et al. J Psychiatr Res. 2018 Jan;96:171-177. doi: 10.1016/j.jpsychires.2017.10.012. Epub 2017 Oct 16. J Psychiatr Res. 2018. PMID: 29078153
In a representative sample (N=8236) of New York City public school students assessed six months after 9/11, latent class analysis was applied to 48 symptoms across seven disorders: posttraumatic stress, agoraphobia, separation anxiety, panic disorde …
In a representative sample (N=8236) of New York City public school students assessed six months after 9/11, latent class analysis was applie …
Phenome-wide diagnostic comparison among suicide deaths and living individuals with chronic pain diagnoses.
DiBlasi E, Kaufman EA, Webster S, Hagn EE, Shabalin AA, Chen D, Han S, Jawish R, Monson ET, Staley MJ, Keeshin BR, Docherty AR, Bakian AV, Okifuji A, Coon H. DiBlasi E, et al. BMC Med. 2024 Dec 2;22(1):568. doi: 10.1186/s12916-024-03794-1. BMC Med. 2024. PMID: 39617899 Free PMC article.
Better characterization of clinical risk profiles and comorbidities across the medical spectrum among people with chronic pain who die by suicide is urgently needed to aid treatment and prevention strategies. ...Utah suicide deaths with chronic pain ha …
Better characterization of clinical risk profiles and comorbidities across the medical spectrum among people wit …