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Comparison of Comet assay dose-response for ethyl methanesulfonate using freshly prepared versus cryopreserved tissues.
Recio L, Kissling GE, Hobbs CA, Witt KL. Recio L, et al. Environ Mol Mutagen. 2012 Mar;53(2):101-13. doi: 10.1002/em.20694. Epub 2011 Nov 8. Environ Mol Mutagen. 2012. PMID: 22069077
The National Toxicology Program (NTP) is using the Comet assay to evaluate genotoxic potential, and is investigating the integration of this assay into repeat-dose toxicity studies. ...For all four tissues, results from frozen, nontransported samples s …
The National Toxicology Program (NTP) is using the Comet assay to evaluate genotoxic potential, and is investigating the integ …
Inter-laboratory comparison of the in vivo comet assay including three image analysis systems.
Plappert-Helbig U, Guérard M. Plappert-Helbig U, et al. Environ Mol Mutagen. 2015 Dec;56(9):788-93. doi: 10.1002/em.21964. Epub 2015 Aug 6. Environ Mol Mutagen. 2015. PMID: 26248301
To compare the extent of potential inter-laboratory variability and the influence of different comet image analysis systems, in vivo comet experiments were conducted using the genotoxicants ethyl methanesulfonate and methyl methanesulfonate. ... …
To compare the extent of potential inter-laboratory variability and the influence of different comet image analysis systems, in vivo …
Validation of Drosophila melanogaster as an in vivo model for genotoxicity assessment using modified alkaline Comet assay.
Siddique HR, Chowdhuri DK, Saxena DK, Dhawan A. Siddique HR, et al. Mutagenesis. 2005 Jul;20(4):285-90. doi: 10.1093/mutage/gei032. Epub 2005 May 17. Mutagenesis. 2005. PMID: 15899934
The single cell gel electrophoresis or Comet assay is one of the most popular techniques for genotoxicity assessment. The present study was undertaken to validate our previously modified version of the Comet assay for genotoxicity assessment in Drosoph …
The single cell gel electrophoresis or Comet assay is one of the most popular techniques for genotoxicity assessment. The pres …
Assessing DNA damage in cnidarians using the Comet assay.
Mitchelmore CL, Hyatt S. Mitchelmore CL, et al. Mar Environ Res. 2004 Aug-Dec;58(2-5):707-11. doi: 10.1016/j.marenvres.2004.03.019. Mar Environ Res. 2004. PMID: 15178102
The assessment of DNA damage by the Comet assay has been described as a useful non-specific general biomarker of stress in many marine organisms. ...Despite this, however, we observed dose responses for each of the study chemicals with no reduction in cell vi …
The assessment of DNA damage by the Comet assay has been described as a useful non-specific general biomarker of stress in man …
Nutritional value of ganoderma extract and assessment of its genotoxicity and antigenotoxicity using comet assays of mouse lymphocytes.
Chiu SW, Wang ZM, Leung TM, Moore D. Chiu SW, et al. Food Chem Toxicol. 2000 Feb-Mar;38(2-3):173-8. doi: 10.1016/s0278-6915(99)00146-5. Food Chem Toxicol. 2000. PMID: 10717357
This extract was assessed for cytotoxicity and in vivo genotoxicity by both acute and subchronic exposure of mice (given by mouth at a dose equivalent to extract of 220g fresh Ganoderma fruit body/kg body weight). To test any alleged protection against mutagens by Ganoderm …
This extract was assessed for cytotoxicity and in vivo genotoxicity by both acute and subchronic exposure of mice (given by mouth at a do
DNA damage induced in human peripheral blood lymphocytes by industrial solid waste and municipal sludge leachates.
Bakare AA, Pandey AK, Bajpayee M, Bhargav D, Chowdhuri DK, Singh KP, Murthy RC, Dhawan A. Bakare AA, et al. Environ Mol Mutagen. 2007 Jan;48(1):30-7. doi: 10.1002/em.20272. Environ Mol Mutagen. 2007. PMID: 17163505
In the present study, leachates of solid wastes from a polyfiber factory (PFL), an aeronautical plant (AEL), and a municipal sludge leachate (MSL) were assessed for their ability to induce DNA damage in human peripheral blood lymphocytes using the alkaline Comet assay
In the present study, leachates of solid wastes from a polyfiber factory (PFL), an aeronautical plant (AEL), and a municipal sludge leachate …