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Comparison of platelet count recovery with use of vincristine and prednisone or prednisone alone for treatment for severe immune-mediated thrombocytopenia in dogs.
Rozanski EA, Callan MB, Hughes D, Sanders N, Giger U. Rozanski EA, et al. J Am Vet Med Assoc. 2002 Feb 15;220(4):477-81. doi: 10.2460/javma.2002.220.477. J Am Vet Med Assoc. 2002. PMID: 11860242 Free article. Clinical Trial.
OBJECTIVE: To evaluate the effect of prednisone alone, compared with a combination of prednisone and vincristine, on platelet counts in bleeding dogs with severe primary immune-mediated thrombocytopenia (IMT). …
OBJECTIVE: To evaluate the effect of prednisone alone, compared with a combination of prednisone and vincristine
Autologous progenitor cell transplantation: prior exposure to stem cell-toxic drugs determines yield and engraftment of peripheral blood progenitor cell but not of bone marrow grafts.
Dreger P, Klöss M, Petersen B, Haferlach T, Löffler H, Loeffler M, Schmitz N. Dreger P, et al. Blood. 1995 Nov 15;86(10):3970-8. Blood. 1995. PMID: 7579368 Free article.
Compared with patients autografted with BM, hematopoietic recovery was significantly accelerated in recipients of PBPC. For PBPC, the number of Dexa-BEAM cycles ( > or = v > 1) was the predominate prognostic factor affecting colony-forming unit-granulocyte-mac …
Compared with patients autografted with BM, hematopoietic recovery was significantly accelerated in recipients of PBPC. For PBPC, the …
Tandem transplants in solid tumors: marrow versus peripheral stem cell transplant: peripheral blood cells as now practiced are not the whole answer.
Spitzer G, Dunphy FR 2nd, Petruska PJ, Velasquez WS, Adkins DR. Spitzer G, et al. J Hematother. 1993 Fall;2(3):363-5. doi: 10.1089/scd.1.1993.2.363. J Hematother. 1993. PMID: 7921997
In conclusion, the use of peripheral blood stem cells alone following sequential high dose CVP is associated with rapid neutrophil and platelet recovery. Caution should be exercised when using PBSC alone after high dose therapy, due to the lack …
In conclusion, the use of peripheral blood stem cells alone following sequential high dose CVP is associated with rapid neutrophil an …