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Complement factor H-related protein 1 deficiency and factor H antibodies in pediatric patients with atypical hemolytic uremic syndrome.
Hofer J, Janecke AR, Zimmerhackl LB, Riedl M, Rosales A, Giner T, Cortina G, Haindl CJ, Petzelberger B, Pawlik M, Jeller V, Vester U, Gadner B, van Husen M, Moritz ML, Würzner R, Jungraithmayr T; German-Austrian HUS Study Group. Hofer J, et al. Clin J Am Soc Nephrol. 2013 Mar;8(3):407-15. doi: 10.2215/CJN.01260212. Epub 2012 Dec 14. Clin J Am Soc Nephrol. 2013. PMID: 23243267 Free PMC article.
BACKGROUND AND OBJECTIVES: This study evaluated the relevance of complement factor H (CFH)-related protein (CFHR) 1 deficiency in pediatric patients with atypical hemolytic uremic syndrome (aHUS) by evaluating …
BACKGROUND AND OBJECTIVES: This study evaluated the relevance of complement factor H (CFH)-related protein (CFHR) 1 …
Atypical hemolytic uremic syndrome associated with complement factor H autoantibodies and CFHR1/CFHR3 deficiency.
Lee BH, Kwak SH, Shin JI, Lee SH, Choi HJ, Kang HG, Ha IS, Lee JS, Dragon-Durey MA, Choi Y, Cheong HI. Lee BH, et al. Pediatr Res. 2009 Sep;66(3):336-40. doi: 10.1203/PDR.0b013e3181b1bd4a. Pediatr Res. 2009. PMID: 19531976
Although genetic defect of complement factor H (CFH) is a common cause of atypical hemolytic uremic syndrome (aHUS), development of autoantibodies to CFH (CFH-Ab) is also known to be an acquired cause of aHUS. ...Screening for CFH- …
Although genetic defect of complement factor H (CFH) is a common cause of atypical hemolytic uremic …
Acquired thrombotic thrombocytopenic purpura with isolated CFHR3/1 deletion-rapid remission following complement blockade.
Bitzan M, Hammad RM, Bonnefoy A, Al Dhaheri WS, Vézina C, Rivard GÉ. Bitzan M, et al. Pediatr Nephrol. 2018 Aug;33(8):1437-1442. doi: 10.1007/s00467-018-3957-8. Epub 2018 May 4. Pediatr Nephrol. 2018. PMID: 29728803 Free PMC article.
He was diagnosed with atypical hemolytic uremic syndrome and treated with a single dose of eculizumab, followed by prompt resolution of all hematological parameters. However, undetectably low plasma ADAMTS13 activity in the pre-treatment sample, associ …
He was diagnosed with atypical hemolytic uremic syndrome and treated with a single dose of eculizumab, followed …
Atypical hemolytic uremic syndrome due to factor H autoantibody.
Uslu-Gökceoğlu A, Doğan CS, Comak E, Koyun M, Akman S. Uslu-Gökceoğlu A, et al. Turk J Pediatr. 2013 Jan-Feb;55(1):86-9. Turk J Pediatr. 2013. PMID: 23692839
Atypical hemolytic uremic syndrome (aHUS) is a disease caused by pathologies in the alternative complement system. ...The subgroup of aHUS designated as DEAP (DEficiency of CFHR Proteins and CFH Autoantibody Positive)-HUS because of autoantibody …
Atypical hemolytic uremic syndrome (aHUS) is a disease caused by pathologies in the alternative complement syste …