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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 2
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2000 7
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2002 16
2003 29
2004 88
2005 124
2006 145
2007 149
2008 128
2009 107
2010 95
2011 85
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1,857 results

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1 article found by citation matching

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Page 1
Computational methodologies for modelling, analysis and simulation of signalling networks.
Gilbert D, Fuss H, Gu X, Orton R, Robinson S, Vyshemirsky V, Kurth MJ, Downes CS, Dubitzky W. Gilbert D, et al. Brief Bioinform. 2006 Dec;7(4):339-53. doi: 10.1093/bib/bbl043. Epub 2006 Nov 20. Brief Bioinform. 2006. PMID: 17116646 Review.
This article is a critical review of computational techniques used to model, analyse and simulate signalling networks. We propose a conceptual framework, and discuss the role of signalling networks in three major areas: signal …
This article is a critical review of computational techniques used to model, analyse and simulate signalling …
Methodologies for the modeling and simulation of biochemical networks, illustrated for signal transduction pathways: a primer.
ElKalaawy N, Wassal A. ElKalaawy N, et al. Biosystems. 2015 Mar;129:1-18. doi: 10.1016/j.biosystems.2015.01.008. Epub 2015 Jan 28. Biosystems. 2015. PMID: 25637875 Review.
Hence, the interest in such networks is growing and they have been the target of several recent modeling efforts. Signal transduction pathways (STPs) constitute a class of biochemical networks that receive, process, and respond to stimuli from t …
Hence, the interest in such networks is growing and they have been the target of several recent modeling efforts. Signal …
Reconstruction of cellular signalling networks and analysis of their properties.
Papin JA, Hunter T, Palsson BO, Subramaniam S. Papin JA, et al. Nat Rev Mol Cell Biol. 2005 Feb;6(2):99-111. doi: 10.1038/nrm1570. Nat Rev Mol Cell Biol. 2005. PMID: 15654321 Review.
The study of cellular signalling over the past 20 years and the advent of high-throughput technologies are enabling the reconstruction of large-scale signalling networks. After careful reconstruction of signalling networks, their properties must …
The study of cellular signalling over the past 20 years and the advent of high-throughput technologies are enabling the reconstructio …
A computational framework for a Lyapunov-enabled analysis of biochemical reaction networks.
Ali Al-Radhawi M, Angeli D, Sontag ED. Ali Al-Radhawi M, et al. PLoS Comput Biol. 2020 Feb 24;16(2):e1007681. doi: 10.1371/journal.pcbi.1007681. eCollection 2020 Feb. PLoS Comput Biol. 2020. PMID: 32092050 Free PMC article.
Complex molecular biological processes such as transcription and translation, signal transduction, post-translational modification cascades, and metabolic pathways can be described in principle by biochemical reactions that explicitly take into account the sophistic …
Complex molecular biological processes such as transcription and translation, signal transduction, post-translational modifica …
Experimental and computational tools for analysis of signaling networks in primary cells.
Schoof EM, Linding R. Schoof EM, et al. Curr Protoc Immunol. 2014 Feb 4;104:11.11.1-11.11.23. doi: 10.1002/0471142735.im1111s104. Curr Protoc Immunol. 2014. PMID: 24510617
Cellular information processing in signaling networks forms the basis of responses to environmental stimuli. At any given time, cells receive multiple simultaneous input cues, which are processed and integrated to determine cellular responses such as migration, prol …
Cellular information processing in signaling networks forms the basis of responses to environmental stimuli. At any given time …
Cerebral cartography and connectomics.
Sporns O. Sporns O. Philos Trans R Soc Lond B Biol Sci. 2015 May 19;370(1668):20140173. doi: 10.1098/rstb.2014.0173. Philos Trans R Soc Lond B Biol Sci. 2015. PMID: 25823870 Free PMC article. Review.
Principal challenges concern the temporal dynamics of functional brain connectivity, the definition of areal parcellations and their hierarchical organization into large-scale networks, the extension of whole-brain connectivity to cellular-scale networks, and the ma …
Principal challenges concern the temporal dynamics of functional brain connectivity, the definition of areal parcellations and their hierarc …
Conceptual and computational framework for logical modelling of biological networks deregulated in diseases.
Montagud A, Traynard P, Martignetti L, Bonnet E, Barillot E, Zinovyev A, Calzone L. Montagud A, et al. Brief Bioinform. 2019 Jul 19;20(4):1238-1249. doi: 10.1093/bib/bbx163. Brief Bioinform. 2019. PMID: 29237040
We present a pipeline of computational tools that performs a series of analyses to explore a logical model's properties. ...We start by analysing the structure of the interaction network constructed from the literature or existing databases. Next, we s …
We present a pipeline of computational tools that performs a series of analyses to explore a logical model's properties …
Dynamic modelling and analysis of biochemical networks: mechanism-based models and model-based experiments.
van Riel NA. van Riel NA. Brief Bioinform. 2006 Dec;7(4):364-74. doi: 10.1093/bib/bbl040. Epub 2006 Nov 14. Brief Bioinform. 2006. PMID: 17107967 Review.
Systems biology applies quantitative, mechanistic modelling to study genetic networks, signal transduction pathways and metabolic networks. ...Current approaches and methods of parameter sensitivity analysis and parameter estimatio …
Systems biology applies quantitative, mechanistic modelling to study genetic networks, signal transduction pathw …
Protein-Protein Interface and Disease: Perspective from Biomolecular Networks.
Hu G, Xiao F, Li Y, Li Y, Vongsangnak W. Hu G, et al. Adv Biochem Eng Biotechnol. 2017;160:57-74. doi: 10.1007/10_2016_40. Adv Biochem Eng Biotechnol. 2017. PMID: 27928579 Review.
With special focus on protein complexes, approaches based on network theory are proposed to meet this challenge. In this review we pay attention to protein-protein interfaces from the perspective of biomolecular networks and their roles in disease. ...We then discus …
With special focus on protein complexes, approaches based on network theory are proposed to meet this challenge. In this review we pa …
Integrated inference and analysis of regulatory networks from multi-level measurements.
Poultney CS, Greenfield A, Bonneau R. Poultney CS, et al. Methods Cell Biol. 2012;110:19-56. doi: 10.1016/B978-0-12-388403-9.00002-3. Methods Cell Biol. 2012. PMID: 22482944 Free PMC article. Review.
Regulatory network inference is the process of inferring these networks, traditionally from microarray data but increasingly incorporating other measurement types such as proteomics, ChIP-seq, metabolomics, and mass cytometry. We discuss existing techniques for n …
Regulatory network inference is the process of inferring these networks, traditionally from microarray data but increasingly i …
1,857 results