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Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B.
Karlsson EK, Sigurdsson S, Ivansson E, Thomas R, Elvers I, Wright J, Howald C, Tonomura N, Perloski M, Swofford R, Biagi T, Fryc S, Anderson N, Courtay-Cahen C, Youell L, Ricketts SL, Mandlebaum S, Rivera P, von Euler H, Kisseberth WC, London CA, Lander ES, Couto G, Comstock K, Starkey MP, Modiano JF, Breen M, Lindblad-Toh K. Karlsson EK, et al. Among authors: comstock k. Genome Biol. 2013 Dec 12;14(12):R132. doi: 10.1186/gb-2013-14-12-r132. Genome Biol. 2013. PMID: 24330828 Free PMC article.
The dog as a cancer model.
Khanna C, Lindblad-Toh K, Vail D, London C, Bergman P, Barber L, Breen M, Kitchell B, McNeil E, Modiano JF, Niemi S, Comstock KE, Ostrander E, Westmoreland S, Withrow S. Khanna C, et al. Among authors: comstock ke. Nat Biotechnol. 2006 Sep;24(9):1065-6. doi: 10.1038/nbt0906-1065b. Nat Biotechnol. 2006. PMID: 16964204 No abstract available.
Efficient mapping of mendelian traits in dogs through genome-wide association.
Karlsson EK, Baranowska I, Wade CM, Salmon Hillbertz NH, Zody MC, Anderson N, Biagi TM, Patterson N, Pielberg GR, Kulbokas EJ 3rd, Comstock KE, Keller ET, Mesirov JP, von Euler H, Kämpe O, Hedhammar A, Lander ES, Andersson G, Andersson L, Lindblad-Toh K. Karlsson EK, et al. Among authors: comstock ke. Nat Genet. 2007 Nov;39(11):1321-8. doi: 10.1038/ng.2007.10. Epub 2007 Sep 30. Nat Genet. 2007. PMID: 17906626
Rethinking dog domestication by integrating genetics, archeology, and biogeography.
Larson G, Karlsson EK, Perri A, Webster MT, Ho SY, Peters J, Stahl PW, Piper PJ, Lingaas F, Fredholm M, Comstock KE, Modiano JF, Schelling C, Agoulnik AI, Leegwater PA, Dobney K, Vigne JD, Vilà C, Andersson L, Lindblad-Toh K. Larson G, et al. Among authors: comstock ke. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8878-83. doi: 10.1073/pnas.1203005109. Epub 2012 May 21. Proc Natl Acad Sci U S A. 2012. PMID: 22615366 Free PMC article.
The domestic dog genome.
Ostrander EA, Comstock KE. Ostrander EA, et al. Curr Biol. 2004 Feb 3;14(3):R98-9. Curr Biol. 2004. PMID: 14986630 Free article. Review. No abstract available.
36 results