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TCR-induced FOXP3 expression by CD8+ T cells impairs their anti-tumor activity.
Lozano T, Conde E, Martín-Otal C, Navarro F, Lasarte-Cia A, Nasrallah R, Alignani D, Gorraiz M, Sarobe P, Romero JP, Vilas A, Roychoudhuri R, Hervás-Stubbs S, Casares N, Lasarte JJ. Lozano T, et al. Among authors: conde e. Cancer Lett. 2022 Mar 1;528:45-58. doi: 10.1016/j.canlet.2021.12.030. Epub 2021 Dec 29. Cancer Lett. 2022. PMID: 34973390
Expansion of Tumor-Infiltrating CD8+ T cells Expressing PD-1 Improves the Efficacy of Adoptive T-cell Therapy.
Fernandez-Poma SM, Salas-Benito D, Lozano T, Casares N, Riezu-Boj JI, Mancheño U, Elizalde E, Alignani D, Zubeldia N, Otano I, Conde E, Sarobe P, Lasarte JJ, Hervas-Stubbs S. Fernandez-Poma SM, et al. Among authors: conde e. Cancer Res. 2017 Jul 1;77(13):3672-3684. doi: 10.1158/0008-5472.CAN-17-0236. Epub 2017 May 18. Cancer Res. 2017. PMID: 28522749
Inflammation and immunity in ovarian cancer.
Salas-Benito D, Vercher E, Conde E, Glez-Vaz J, Tamayo I, Hervas-Stubbs S. Salas-Benito D, et al. Among authors: conde e. EJC Suppl. 2020 Aug 22;15:56-66. doi: 10.1016/j.ejcsup.2019.12.002. eCollection 2020 Aug. EJC Suppl. 2020. PMID: 33240443 Free PMC article.
The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes.
Salas-Benito D, Conde E, Tamayo-Uria I, Mancheño U, Elizalde E, Garcia-Ros D, Aramendia JM, Muruzabal JC, Alcaide J, Guillen-Grima F, Minguez JA, Amores-Tirado J, Gonzalez-Martin A, Sarobe P, Lasarte JJ, Ponz-Sarvise M, De Andrea CE, Hervas-Stubbs S. Salas-Benito D, et al. Among authors: conde e. Br J Cancer. 2021 Mar;124(6):1138-1149. doi: 10.1038/s41416-020-01218-4. Epub 2021 Jan 5. Br J Cancer. 2021. PMID: 33402737 Free PMC article.
Epitope spreading driven by the joint action of CART cells and pharmacological STING stimulation counteracts tumor escape via antigen-loss variants.
Conde E, Vercher E, Soria-Castellano M, Suarez-Olmos J, Mancheño U, Elizalde E, Rodriguez ML, Glez-Vaz J, Casares N, Rodríguez-García E, Hommel M, González-Aseguinolaza G, Uranga-Murillo I, Pardo J, Alkorta G, Melero I, Lasarte J, Hervas-Stubbs S. Conde E, et al. J Immunother Cancer. 2021 Nov;9(11):e003351. doi: 10.1136/jitc-2021-003351. J Immunother Cancer. 2021. PMID: 34810235 Free PMC article.
Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells.
Martín-Otal C, Lasarte-Cia A, Serrano D, Casares N, Conde E, Navarro F, Sánchez-Moreno I, Gorraiz M, Sarrión P, Calvo A, De Andrea CE, Echeveste J, Vilas A, Rodriguez-Madoz JR, San Miguel J, Prosper F, Hervas-Stubbs S, Lasarte JJ, Lozano T. Martín-Otal C, et al. Among authors: conde e. J Immunother Cancer. 2022 Aug;10(8):e004479. doi: 10.1136/jitc-2021-004479. J Immunother Cancer. 2022. PMID: 35918123 Free PMC article.
Gemcitabine-mediated depletion of immunosuppressive dendritic cells enhances the efficacy of therapeutic vaccination.
Repáraz D, Ruiz M, Silva L, Aparicio B, Egea J, Guruceaga E, Ajona D, Senent Y, Conde E, Navarro F, Barace S, Alignani D, Hervás-Stubbs S, Lasarte JJ, Llopiz D, Sarobe P. Repáraz D, et al. Among authors: conde e. Front Immunol. 2022 Oct 10;13:991311. doi: 10.3389/fimmu.2022.991311. eCollection 2022. Front Immunol. 2022. PMID: 36300124 Free PMC article.
Nigrostriatal degeneration determines dynamics of glial inflammatory and phagocytic activity.
Ayerra L, Abellanas MA, Basurco L, Tamayo I, Conde E, Tavira A, Trigo A, Vidaurre C, Vilas A, San Martin-Uriz P, Luquin E, Clavero P, Mengual E, Hervás-Stubbs S, Aymerich MS. Ayerra L, et al. Among authors: conde e. J Neuroinflammation. 2024 Apr 12;21(1):92. doi: 10.1186/s12974-024-03091-x. J Neuroinflammation. 2024. PMID: 38610019 Free PMC article.
Microglia and astrocyte activation is region-dependent in the α-synuclein mouse model of Parkinson's disease.
Basurco L, Abellanas MA, Ayerra L, Conde E, Vinueza-Gavilanes R, Luquin E, Vales A, Vilas A, Martin-Uriz PS, Tamayo I, Alonso MM, Hernaez M, Gonzalez-Aseguinolaza G, Clavero P, Mengual E, Arrasate M, Hervás-Stubbs S, Aymerich MS. Basurco L, et al. Among authors: conde e. Glia. 2023 Mar;71(3):571-587. doi: 10.1002/glia.24295. Epub 2022 Nov 10. Glia. 2023. PMID: 36353934 Free PMC article.
313 results