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Year Number of Results
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1980 5
1981 5
1982 7
1983 15
1984 6
1985 11
1986 12
1987 8
1988 22
1989 31
1990 25
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1992 27
1993 40
1994 46
1995 53
1996 54
1997 81
1998 82
1999 99
2000 107
2001 108
2002 122
2003 150
2004 165
2005 178
2006 209
2007 264
2008 278
2009 276
2010 311
2011 370
2012 407
2013 446
2014 475
2015 548
2016 601
2017 664
2018 662
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12,377 results

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Page 1
Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial.
Su X, Meng ZT, Wu XH, Cui F, Li HL, Wang DX, Zhu X, Zhu SN, Maze M, Ma D. Su X, et al. Lancet. 2016 Oct 15;388(10054):1893-1902. doi: 10.1016/S0140-6736(16)30580-3. Epub 2016 Aug 16. Lancet. 2016. PMID: 27542303 Free article. Clinical Trial.
The primary endpoint was the incidence of delirium, assessed twice daily with the Confusion Assessment Method for intensive care units during the first 7 postoperative days. ...FINDINGS: Between Aug 17, 2011, and Nov 20, 2013, of 2016 patients asses …
The primary endpoint was the incidence of delirium, assessed twice daily with the Confusion Assessment Method fo …
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness.
Girard TD, Exline MC, Carson SS, Hough CL, Rock P, Gong MN, Douglas IS, Malhotra A, Owens RL, Feinstein DJ, Khan B, Pisani MA, Hyzy RC, Schmidt GA, Schweickert WD, Hite RD, Bowton DL, Masica AL, Thompson JL, Chandrasekhar R, Pun BT, Strength C, Boehm LM, Jackson JC, Pandharipande PP, Brummel NE, Hughes CG, Patel MB, Stollings JL, Bernard GR, Dittus RS, Ely EW; MIND-USA Investigators. Girard TD, et al. N Engl J Med. 2018 Dec 27;379(26):2506-2516. doi: 10.1056/NEJMoa1808217. Epub 2018 Oct 22. N Engl J Med. 2018. PMID: 30346242 Free PMC article. Clinical Trial.
BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute respiratory failure or shock and h …
BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). …
Use of the confusion assessment method in multicentre delirium trials: training and standardisation.
Green JR, Smith J, Teale E, Collinson M, Avidan MS, Schmitt EM, Inouye SK, Young J. Green JR, et al. BMC Geriatr. 2019 Apr 15;19(1):107. doi: 10.1186/s12877-019-1129-8. BMC Geriatr. 2019. PMID: 30991945 Free PMC article. Clinical Trial.
Multicentre clinical trials evaluating interventions to prevent delirium are needed. The Confusion Assessment Method (CAM) is a validated instrument for delirium detection. We hypothesised it would be possible for a large feasibility study to train a large nu …
Multicentre clinical trials evaluating interventions to prevent delirium are needed. The Confusion Assessment Method (C …
Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial.
Riker RR, Shehabi Y, Bokesch PM, Ceraso D, Wisemandle W, Koura F, Whitten P, Margolis BD, Byrne DW, Ely EW, Rocha MG; SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group. Riker RR, et al. JAMA. 2009 Feb 4;301(5):489-99. doi: 10.1001/jama.2009.56. Epub 2009 Feb 2. JAMA. 2009. PMID: 19188334 Clinical Trial.
DESIGN, SETTING, AND PATIENTS: Prospective, double-blind, randomized trial conducted in 68 centers in 5 countries between March 2005 and August 2007 among 375 medical/surgical ICU patients with expected mechanical ventilation for more than 24 hours. Sedation level and delirium we …
DESIGN, SETTING, AND PATIENTS: Prospective, double-blind, randomized trial conducted in 68 centers in 5 countries between March 2005 and Aug …
Detection of postoperative delirium by family and caregivers: Evaluation of the family confusion assessment method (FAM-CAM).
Mickle AM, Tellor Pennington BR, Abdallah AB, Wang W, Lin N, Oberhaus J, Budelier TP, Park D, Palanca BJ, Wildes TS, Schmitt EM, Inouye SK, Avidan MS. Mickle AM, et al. J Clin Anesth. 2025 Sep;106:111963. doi: 10.1016/j.jclinane.2025.111963. Epub 2025 Aug 13. J Clin Anesth. 2025. PMID: 40812167 Free PMC article. Clinical Trial.
In the hospital, delirium was ascertained using the Confusion Assessment Method (CAM) long-form or the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU), and structured chart review. Family members completed a Family Co …
In the hospital, delirium was ascertained using the Confusion Assessment Method (CAM) long-form or the Confusion …
The Confusion Assessment Method for the ICU-7 Delirium Severity Scale: A Novel Delirium Severity Instrument for Use in the ICU.
Khan BA, Perkins AJ, Gao S, Hui SL, Campbell NL, Farber MO, Chlan LL, Boustani MA. Khan BA, et al. Crit Care Med. 2017 May;45(5):851-857. doi: 10.1097/CCM.0000000000002368. Crit Care Med. 2017. PMID: 28263192 Free PMC article.
MEASUREMENTS AND MAIN RESULTS: Patients received the Confusion Assessment Method for the ICU, Richmond Agitation-Sedation Scale, and Delirium Rating Scale-Revised-98 assessments. ...Higher Confusion Assessment Method for the ICU-7 …
MEASUREMENTS AND MAIN RESULTS: Patients received the Confusion Assessment Method for the ICU, Richmond Agitation-Sedati …
Prophylactic melatonin for delirium in intensive care (Pro-MEDIC): a randomized controlled trial.
Wibrow B, Martinez FE, Myers E, Chapman A, Litton E, Ho KM, Regli A, Hawkins D, Ford A, van Haren FMP, Wyer S, McCaffrey J, Rashid A, Kelty E, Murray K, Anstey M. Wibrow B, et al. Intensive Care Med. 2022 Apr;48(4):414-425. doi: 10.1007/s00134-022-06638-9. Epub 2022 Feb 27. Intensive Care Med. 2022. PMID: 35220473 Clinical Trial.
The primary outcome was the proportion of delirium-free assessments, as a marker of delirium prevalence, within 14 days or before ICU discharge. Delirium was assessed twice daily using the Confusion Assessment Method for ICU (CAM-ICU) score. Sec …
The primary outcome was the proportion of delirium-free assessments, as a marker of delirium prevalence, within 14 days or before ICU …
Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018.
Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG; Nomenclature Consensus Working Group. Evered L, et al. Br J Anaesth. 2018 Nov;121(5):1005-1012. doi: 10.1016/j.bja.2017.11.087. Epub 2018 Jun 15. Br J Anaesth. 2018. PMID: 30336844 Free PMC article. Review.
Research into cognitive change after anaesthesia and surgery accelerated in the 1980s when multiple studies utilised detailed neuropsychological testing for assessment of cognitive change after cardiac surgery. This body of work consistently documented decline in cognitive …
Research into cognitive change after anaesthesia and surgery accelerated in the 1980s when multiple studies utilised detailed neuropsycholog …
Prospective Validation of the Preschool Confusion Assessment Method for the ICU to Screen for Delirium in Infants Less Than 6 Months Old.
Canter MO, Tanguturi YC, Ellen Wilson J, Williams SR, Exum SA, Umrania HM, Betters KA, Raman R, Ely EW, Pandharipande PP, Fuchs DC, Smith HAB. Canter MO, et al. Crit Care Med. 2021 Oct 1;49(10):e902-e909. doi: 10.1097/CCM.0000000000005099. Crit Care Med. 2021. PMID: 34166285
DESIGN: Prospective cohort study to validate the Preschool Confusion Assessment Method for the ICU for the assessment of ICU delirium in neonates and young infants compared with the reference standard, Child and Adolescent Psychiatry. ...A total of 189 …
DESIGN: Prospective cohort study to validate the Preschool Confusion Assessment Method for the ICU for the assessmen …
Effect of Remimazolam on Emergence Delirium in Children Undergoing Laparoscopic Surgery: A Double-blinded Randomized Trial.
Cai YH, Zhong JW, Ma HY, Szmuk P, Wang CY, Wang Z, Zhang XL, Dong LQ, Liu HC. Cai YH, et al. Anesthesiology. 2024 Sep 1;141(3):500-510. doi: 10.1097/ALN.0000000000005077. Anesthesiology. 2024. PMID: 38758221 Free PMC article. Clinical Trial.
This study investigated the hypothesis that a continuous infusion or a single bolus of remimazolam can reduce the incidence of emergence delirium in children. METHODS: A total of 120 children aged 1 to 6 yr were randomly and equally allocated into three groups: group RC, w …
This study investigated the hypothesis that a continuous infusion or a single bolus of remimazolam can reduce the incidence of emergence del …
12,377 results
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